Holistic Approach for Active and Healthy Aging: Physical and Cognitive Activity, and Nutrition
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 77
- 试验地点
- 2
- 主要终点
- Change in gait speed
研究概览
简要总结
Within this project the investigators tested the effectiveness of 2-month of computerized cognitive training (CCT) on CogniFit online platform on 77 older adults, which were randomly divided into intervention and control group. The investigators tested close (battery of cognitive functions) and far transfer (postural and mobility control, EEG, blood samples) of the CCT. Additionally, the investigators were interested into seeing a long-lasting effect, therefore participants were brought back to the laboratory 1 year post CCT.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
盲法说明
A single-blind randomized controlled trial
入排标准
- 年龄范围
- 60 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •active and healthy older adults with no major health issues
- •members of the Center for Daily Activity Koper (Slovenia)
- •had normal or corrected-to-normal vision;
- •reported no history of cardiovascular, neurological, or psychiatric conditions
排除标准
- •younger than 60
- •smoking; regular alcohol consumption;
- •acute or chronic skeletal, neuromuscular, metabolic and cardiovascular disease condition;
研究组 & 干预措施
Intervention group
Participants in the intervention group received 24 sessions of computerized cognitive training, with a total time of 960 min.
干预措施: Computerized cognitive training (Other)
Active control group
Participants in the control group attended activities separate activities, such as learning about healthy lifestyle, had cooking and other social lessons for the same amount as the intervention group performed cognitive training.
干预措施: Computerized cognitive training (Other)
结局指标
主要结局
Change in gait speed
时间窗: up to 8 weeks
The primary outcome is change in gait speed during single- and dual-task conditions from baseline to post-intervention.
次要结局
- Executive control (Trail-Making Task Forms A and B)(up to 8 weeks)
- Sensorimotor integration measured with EEG/ERP methodology(up to 8 weeks)
- Brain-derived neurotrophic factor (BDNF) extracted from peripheral blood sampling(up to 8 weeks)