Pilot Study of Geriatric Assessments in Senior Adults With Multiple Myeloma
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 42
- 试验地点
- 1
- 主要终点
- The relationship between initial treatment recommendation and baseline questionnaires assessment
研究概览
简要总结
This study will evaluate the prevalence of geriatric syndromes in older adults with multiple myeloma, examine relationships between baseline geriatrics syndromes and initial treatment selection, and examine risk of functional decline.
Relationship between baseline geriatric questionnaires and initial treatment selection in older adults with newly diagnosed multiple myeloma.
Feasibility of subjects completing the CARG geriatric assessments at baseline, 3 months and 6 months.
Comorbidities or dependence in IADLs at baseline predict decline in functional status at 6 months of follow-up in older adults with newly diagnosed multiple myeloma.
研究设计
- 研究类型
- Observational
- 时间视角
- Prospective
入排标准
- 年龄范围
- 65 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patient must have a diagnosis of multiple myeloma by IMWF criteria: diagnosis must have occurred within 3 months of study enrollment.
- •Patient must be ≥ 65 years of age.
- •Patient's life expectancy must be ≥ 6 months.
- •Patient must be willing to complete follow-up assessments.
- •Patient must be able to understand and willing to sign a written informed consent document.
排除标准
- •Patient must not have a diagnosis of smoldering myeloma.
- •Patient must not have concomitant amyloidosis.
结局指标
主要结局
The relationship between initial treatment recommendation and baseline questionnaires assessment
时间窗: At baseline visit
The physician caring for the patient will be asked to identify his/her initial treatment recommendations. This includes whether the patient is, in his/her assessment, a candidate for high dose therapy and autologous stem cell transplantation. It will also include whether a 2-drug or 3-drug regimen is recommended initially.
次要结局
- Changes in questionnaires from baseline to 6 months(Through 6 months of follow-up)
- Completion of the questionnaires at baseline, 3 months and 6 months.(Baseline, 3 months, and 6 months)