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临床试验/NCT03017365
NCT03017365已完成不适用

Effects of Different Resistance Training Methods on Strength, Motor Control and Executive Functions in Older Adults

University of Kassel0 个研究点目标入组 82 人开始时间: 2017年1月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
82
主要终点
Clinical Gait Analysis

研究概览

简要总结

It is well documented that both balance and resistance training have the potential to mitigate intrinsic fall risk factors in older adults. Recently, it was shown that a simultaneously executed balance and resistance training, namely resistance training on uneven surfaces is an eligible, effective and safe alternative training program to mitigate intrinsic fall risk factors in older adults. However, knowledge about the effects of specific adductor and abductor training has advantages over traditional resistance training and resistance training on unstable surfaces regarding forward propulsion. Further, the effects of different kinds of resistance training on cognition, especially embodiment is investigated.

详细描述

Introduction: In the course of ageing, physical abilities decline and consequently there is an increase in risk of falling and fall incidences. Notwithstanding, the fact that causes of falls are multifactorial, losses in lower-extremity muscle strength, power and balance seem to be the most prominent intrinsic (i.e., person-related) fall risk factors in older adults. Several systematic reviews and meta-analyses highlighted the positive effects of resistance and balance training when applied as a single means, on measures of leg muscle strength, power and balance in older adults. Recently, it was shown that a simultaneously executed balance and resistance training, namely resistance training on uneven surfaces is an eligible, effective and safe alternative training program to mitigate intrinsic fall risk factors in older adults. Based on several investigations, it can be safely assumed that exercises conducted on unstable devices activate smaller muscles and stabilising function of bigger muscle groups. This facilitates torque and power transfer from lower to upper extremeties and is possibly responsible for similar effects as compared to stable resistance training despite lower loads. However, it is unknown if resistance training targeting adductor and abductor muscles induces similar results as compared to resistance training conducted on uneven surfaces. Moreover, physical activity has proven to affect cognitive measures positively, especially executive functions. It has yet to be determined to what extent different kinds of resistance training affect executive functions.

Methods/Design: This study is a three-arm, 10-week RCT with a 10-week no-contact follow-up. Participants were randomly allocated (1:1) to either: 1) machine-based stable resistance training (M-SRT); 2) free-weight unstable resistance training (F-URT); 3) machine-based adductor and abductor resistance training. The design and reporting of this study follows the CONSORT (Consolidated Standards of Reporting Trials) 2010 Statement for parallel group randomised trials.

Setting Participants are recruited from the communities in and around Kassel, Germany. Screening visits, measurement sessions, and the interventions are held at the Insitute of Sports and Sports Science / University of Kassel, Germany.

Recruitment strategies: Recruitment is carried out by placing 1) an advertisement in the local newspaper, 2) during a public information meeting at the local town hall and 3) word of mouth. Interested individuals contact the study coordinator by phone, where they are provided with a brief description of the study. If responses suggest study eligibility then interested individuals are invited to attend a formal in-person screening visit.

Participants:Older adults are eligible if they: 1) are aged between 65 and 80 years old 2) and able to walk independently for more than 10m. An a priori power analysis using G*Power 3.1 with an assumed type I error of .05 and a type II error of .10 (90% statistical power, correlation among groups: .5, nonsphericity correction: 1) was computed to determine an appropriate sample size to detect medium (.50 ≤ d ≤ .79) interaction effects. The calculations were based on a study assessing the effects of core strength training using unstable devices on older adults. The analysis revealed the requirement of 54 participants (18 per group) to obtain medium "time x group" interaction effects. Considering the likelihood of dropouts, at least 83 participants are going to be recruited to compensate for a possible dropout rate of ~20%.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Single (Outcomes Assessor)

入排标准

年龄范围
65 Years 至 80 Years(Older Adult)
性别
All
接受健康志愿者

入选标准

  • between 65 and 80 years old
  • ability to walk independently without any gait aid

排除标准

  • pathological ratings of the Clock Drawing Test (CDT),
  • Mini-Mental-State-Examination (MMSE, < 24 points),
  • Falls Efficacy Scale - International (FES-I, > 24 points),
  • Geriatric Depression Scale (GDS, > 9 points),
  • Freiburg Questionnaire of Physical Activity (FQoPA, < 1hour)
  • Frontal Assessment Battery (FAB-D, < 18 points)
  • any neurological, musculoskeletal or heart-related disease

研究组 & 干预措施

M-SRT

Active Comparator

Machine-based stable resistance training. Exercising 'traditional' machine-based resistance training.

干预措施: Stable Resistance Training (Other)

F-URT

Experimental

Free weight unstable resistance training; conducted free-weight resistance training on unstable devices using dumbbells instead of exercise-machines.

干预措施: Unstable Resistance Training (Other)

M-ART

Experimental

Machine-based adductor/abductor resistance training. Exercising with 'traditional' adductor/abductor machines.

干预措施: Adductor/Abductor Resistance Training (Other)

结局指标

主要结局

Clinical Gait Analysis

时间窗: Pre test -> Intervention (10 weeks) -> Post test (within 2-5 days after the intervention)

changes in variance components (Vucm, Vort, Vtot) of an uncontrolled manifold analysis; measured in rad²

次要结局

  • Proactivec Balance (timed up and go test)(Pre test -> Intervention (10 weeks) -> Post test (within 2-5 days after the intervention))
  • Maximal isometric adductor and abductor strength(Pre test -> Intervention (10 weeks) -> Post test (within 2-5 days after the intervention))
  • Stroop Task(Pre test -> Intervention (10 weeks) -> Post test (within 2-5 days after the intervention))
  • Proactivec Balance (multidirectional reach test)(Pre test -> Intervention (10 weeks) -> Post test (within 2-5 days after the intervention))
  • Fall self-efficacy Questionnaire(Pre test -> Intervention (10 weeks) -> Post test (within 2-5 days after the intervention))
  • Power tests (chair rise test)(Pre test -> Intervention (10 weeks) -> Post test (within 2-5 days after the intervention))
  • Maximal isometric leg extension strength (ILES)(Pre test -> Intervention (10 weeks) -> Post test (within 2-5 days after the intervention))

研究者

发起方
University of Kassel
申办方类型
Other
责任方
Sponsor

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