To Study the safety and efficacy of intravenous Estrogen as therapeutic adjunct for treatment of hemorrhagic shock patient presenting to the emergency department of a level 1 trauma centre - REST - Trial

Indian Council of Medical Research0 个研究点目标入组 40 人开始时间: 待定最近更新: 2021年11月24日

试验速览

暂无简介。

•Trauma victims
•Systolic Blood pressure (SBP) of <=90mmHg.
•Estimated time to study drug administration <8hrs post trauma
•Glasgow coma scale (GCS) score of between 3 and 8 prior to intubations and/or sedation, due to difficulty of patients cooperation in assessment after these intervention

•Age: Less than 18 years
•Known incarcerated individual
•Cardiopulmonary resuscitation (CPR) prior to study drug administration
•Known contraindication for estrogen (male sex is NOT a contraindication)
•Patients already resuscitated with colloids or crystalloids before reporting to the emergency department.
•Pregnant lady
•Non hemorrhagic-shock:
•1- Tension pnumothorax
•3- Neurogenic
•Previous history of thrombosis events such as DVT (Deep venous thrombosis)
•Injury time unknown
•Drug Medication:
•1.Intravenous drug abuse
•2.oral contraceptive
•3.Estrogen
•4.Heparin induced thrombocytopenia

发起方