Analgetic Effect of Nitrousoxide-oxygen Inhalation for Dental Treatment of Children
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 56
- 试验地点
- 1
- 主要终点
- Dental pain (pulp) threshold
研究概览
简要总结
To assess the analgetic effect of nitrousoxide-oxygen inhalation on pain perception in 12-15 years old children from 1) the dental pulp; 2) the masseter muscle; 3) the skin on the upper lip
详细描述
The present study is a randomized, cross-over blinded study on the analgetic effect of nitrousoxide-oxygen on sensitivity of the dental pulp, the skin and muscles.
It is conducted in healthy 12-15 year old Danish children attending public schools in the municipality of Aarhus, Denmark
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 12 Years 至 15 Years（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •ASA-groups I or II
- •12-15 year of age
- •sound upper central incisors
排除标准
- •difficulties breathing through the nose
- •pregnancy
- •trauma to test teeth
研究组 & 干预措施
Arm 1
Inhalation of nitrousoxide-oxygen during the first experimental session; inhalation of atmospheric air during the second session
干预措施: Nitrousoxide-oxygen and atmospheric air (Drug)
Arm 2
Inhalation of atmospheric air during the first experimental session; inhalation of nitrousoxide-oxygen during the second session
干预措施: Atmospheric air; nitrousoxide-oxygen (Drug)
结局指标
主要结局
Dental pain (pulp) threshold
时间窗: During and after inhalation
次要结局
- Muscle sensitivity to pressure(During and after inhalation)
- Skin sensitivity ot electric stimulation(During and after inhalation)