The Effect of Placental Cord Drainage on Postpartum Blood Loss
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 71
- 试验地点
- 1
- 主要终点
- Qualitative Blood Loss
研究概览
简要总结
To determine if placental cord drainage decreases the blood loss after spontaneous vaginal delivery
详细描述
Postpartum hemorrhage complicates 3% of pregnancies in the United States and is a leading cause of maternal morbidity and mortality. ACOG defines PPH as cumulative blood loss greater than 1000cc; however a blood loss >500cc should be considered abnormal. Primary PPH occurs in the first 24 hours and is largely secondary to uterine agony. ACOG as well as the WHO recommend active management of the third stage of labor to prevent PPH. This includes oxytocin administration, uterine massage, and gentle cord traction. Placental cord drainage (PCD) is the unclamping of the umbilical cord to allow for drainage of the blood from the placenta. It is another technique used to shorten the third stage of labor; however, it has not been well studied
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Singleton Gestation
- •Ages 18-45
- •English Speaking
- •Third Trimester Gestation
排除标准
- •Operative Vaginal Delivery
- •Multiple Gestation
- •Cesarean Delivery
- •Episiotomy
- •3rd or 4th degree laceration
- •Less than the Third Trimester of Pregnancy
- •Chorioamnionitis
- •History of Postpartum Hemorrhage
- •Macrosomic Infant
研究组 & 干预措施
Placenta Blood Drained
Immediately after delayed cord clamping and cutting of the umbilical cord, the cord will be unclamped and blood with be drained until cessation of flow.
干预措施: Placental Blood Drainage (Procedure)
Placenta Blood Not Drained
This is the control group. The cord will not be unclamped.
干预措施: Placenta Blood Not Drained (Procedure)
结局指标
主要结局
Qualitative Blood Loss
时间窗: Through delivery completion, on average 30 minutes
Total Volume in Underbuttocks Drape - Initial Volume in Drape (amniotic fluid etc) + blood in laparotomy sponges
次要结局
- Blood Loss > 500 cc(30 minutes to 1 hour after delivery)
- Need for Blood Transfusion(Up to 24 hours postpartum)
- Duration of Third Stage of Labor(On average 30 minutes)
- Postpartum Hemorrhage(30 minutes to 1 hour after delivery)
- Retained Placenta(30 minutes after delivery)
- Percent Drop in HgB and Hct(Up to 48 hours following delivery)
- Additional Uterotonic Administration(30 minutes to 1 hour following delivery)
- Endometritis(Up to 12 weeks following delivery)