NCT02616835已完成不适用
Investigating the Physiology of Targeted Theta-burst Neuromodulation
Institute of Mental Health Nottingham2 个研究点 分布在 1 个国家目标入组 28 人开始时间: 2014年8月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 28
- 试验地点
- 2
- 主要终点
- Changes in functional connectivity following TMS administration using functional MRI
研究概览
简要总结
This research seeks to study the physiological effects of theta-burst transcranial magnetic stimulation (TMS) in the brains of healthy controls using functional MRI and spectroscopy.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •No personal history of neurological or psychiatric disorders
排除标准
- •Have had a brain injury or neurological disorder
- •Have ever suffered an epileptic fit
- •Have any non-removable metal implants
- •Drink more than 20 units of alcohol per week on a regular basis
- •Currently take any illicit drugs on regular basis
- •Likely to be pregnant
- •Ever suffered from a serious mental illness such as schizophrenia, severe depression or bipolar disorder
- •Currently take any psychotropic medication
结局指标
主要结局
Changes in functional connectivity following TMS administration using functional MRI
时间窗: One hour
Changes in brain connectivity will be assessed by comparing functional MRI scans after theta-burst TMS and sham theta-burst TMS
次要结局
- Changes in brain metabolites following TMS administration using MR spectroscopy(One hour)
研究者
Sarina Iwabuchi
Dr Sarina Iwabuchi
Institute of Mental Health Nottingham
研究点 (2)
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