跳至主要内容
临床试验/NCT06413160
NCT06413160尚未招募不适用

The Cardiovascular-Renal-Metabolic (CRM) Syndrome Survey in Jordan

Jordan Collaborating Cardiology Group1 个研究点 分布在 1 个国家目标入组 10,000 人开始时间: 2026年7月1日最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
10,000
试验地点
1
主要终点
Prevalence of cardiovascular-renal-metabolic syndrome

研究概览

简要总结

Cardiovascular-renal-metabolic (CRM) syndrome is defined as a systemic disorder with a collection of related signs and symptoms attributable to the coexistence of multiple cardiovascular, renal and metabolic disease with a common underlying pathophysiology in one individual. Surveying this syndrome in a large population in Jordan aims at studying the risk factors, components and stages of the syndrome, thus helping early screening, diagnosing and treating disease and its risk factors.

详细描述

Cardiovascular-renal-metabolic (CRM) syndrome is defined as a systemic disorder with a collection of related signs and symptoms attributable to the coexistence of multiple cardiovascular, renal and metabolic disease with a common underlying pathophysiology in one individual.

CRM syndrome reflects the intersection of cardiovascular disease with chronic kidney disease (CKD), and metabolic disease and risk factors (RF). A critical combination of these diseases and their risk factors in the same individual has a profound impact on quality of life and overall mortality. The clinical implications of the presence of CRM are significant, with premature morbidity and mortality, multiple organ-system disease, and high health care budgets mainly driven by the burden of cardiovascular disease (CVD).

There are high prevalence rates of all components of CRM and its RF on a global level and in the Middle East. Of note is the high prevalence of CV in the young, smoking, diabetes mellitus, obesity and dyslipidemia.

The current study will evaluate the prevalence of components and RF of CRM disease in a large population in North, central and South of Jordan.

In the Middle East, no systematic study has evaluated the definition of CRM, definition of its stages, and prevalence of its RF and its relation to the coexisting social determinants of health.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Adults (age 18 years and above).
  • Willing to sign an informed consent.

排除标准

  • 未提供

结局指标

主要结局

Prevalence of cardiovascular-renal-metabolic syndrome

时间窗: From date of study entry through study completion, an average of 1 year

1. CVD A. Coronary heart disease: Silent and clinical CAD (chronic stable coronary disease, acute coronary disease \[ST-elevation myocardial infarction and non-ST-elevation acute coronary syndrome\]. B. Heart failure. C. Atrial fibrillation. D. Stroke. E. Peripheral artery disease 2. Renal: chronic kidney disease 3. Metabolic: A. Obesity/ B. Diabetes mellitus (DM).

次要结局

  • Elevated levels of blood markers(From date of study entry through study completion, an average of 1 year)

研究者

发起方
Jordan Collaborating Cardiology Group
申办方类型
Other
责任方
Principal Investigator
主要研究者

Ayman J Hammoudeh, MD, FACC

Director, Department of Clinical Research

Jordan Collaborating Cardiology Group

研究点 (1)

Loading locations...

相似试验