NCT00635739已完成不适用
Efficacy of Whey Protein Supplementation on Resistance Exercise-Induced Changes in Muscle Strength, Fat Free Mass, and Function in Mobility-Limited Older Adults
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 80
- 试验地点
- 2
- 主要终点
- 1 Repetition Maximum Muscle Strength 1-RM (N) Double Leg Press
研究概览
简要总结
This research study is looking at the effects of a whey protein nutritional supplement on changes in muscle mass, strength and physical function in response to a 6 month program of strength training exercise.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Care Provider, Investigator)
入排标准
- 年龄范围
- 70 Years 至 85 Years（Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Male and Females 70-85 yrs
- •Community dwelling
- •Short Physical Performance Battery score < 10
- •BMI = 21-32.5
排除标准
- •Acute or terminal illness
- •Mini Mental State Exam < 23
- •Myocardial infarction in previous 6 months, symptomatic coronary artery disease, or congestive heart failure
- •Upper or lower extremity fracture in previous 6 months
- •Uncontrolled hypertension (>150/90 mm Hg).
- •Neuromuscular diseases and drugs which affect neuromuscular function.
- •Hormone replacement therapy
- •eGFR <30 mL/min/1.73m2
- •Types I and II Diabetes Mellitus
- •Dietary protein intake < 0.8 g.kg-1.day-1
- •Disorders of nutrient absorption
- •Milk, or whey allergy
- •Sulfa drugs and allergy to PABA-containing sunscreens
研究组 & 干预措施
A, 2
Placebo Comparator
干预措施: Maltodextrin placebo (Dietary Supplement)
A, 1
Active Comparator
干预措施: Whey protein (Dietary Supplement)
结局指标
主要结局
1 Repetition Maximum Muscle Strength 1-RM (N) Double Leg Press
时间窗: Baseline and follow up (6 months)
The maximum muscle strength of the leg extensor muscles as measured by pneumatic strength training equipment.
次要结局
- Lean Mass(Baseline and follow up (6 months))
研究者
Roger A Fielding
Director and Senior Scientist, Professor of Nutrition, Jean Mayer USDA Human Nutrition Research Center on Aging.
Tufts University
研究点 (2)
Loading locations...
相似试验
已完成
不适用
Whey Protein Supplementation Associated With Resistance Training on Health Indicators in Trained Older WomenBody CompositionHealthyNCT03247192Universidade Estadual de Londrina66
已完成
不适用
Whey Protein Supplementation in High School AthletesBody Weight ChangesAthletic PerformanceRecoverySleepNCT05589129University of Utah31
已完成
不适用
Whey Protein Supplementation and Resistance Training in Older Women With Sarcopenic Obesity.Body WeightHealthyNCT03752359Universidade Estadual de Londrina26
已完成
不适用
Strength-enhancing Effect of Whey Protein Supplementation Following Resistance Exercise in Adolescent MalesHealthyNCT02162459Olympia Eye Clinic18
已完成
2 期
Nutritional Intervention in Children With Autism Using Whey Protein (Immunocal): Impact on Core Areas of BehaviorAutism Spectrum DisordersNCT01366859Nova Southeastern University81