Proinflammatory mediators in fibromyalgia syndrome and their modulation by a multimodal therapeutic program - FMS-Eicos

Klinik für Physikalische Medizin und Rehabilitation0 个研究点目标入组 174 人开始时间: 2023年5月9日最近更新: 2024年8月19日

适应症

试验速览

暂无简介。

•diagnosis of fibromyalgia according to ACR criteria (patients)
•No pain in the last four weeks before participation in the study (healthy subjects)
•participation in the day clinic focus on osteoarthritis, back pain or osteoporosis of the Clinic and Polyclinic for Physical Medicine and Rehabilitation and continuous pain VAS>3/ 10 on the visual analog scale (VAS) from 0-10 for more than 3 months (patient control group)
•willingness to give a blood sample as part of the study
•wllingness to refrain from taking NSAIDs and COX inhibitors from 1 week prior to and during the observation period
•no intake of paracetamol and metamizole up to 3 days before the blood samples (patient diary)

•Age under 18 years
•lack of compliance
•Pregnancy or breastfeeding period (anamnestic clarification according to CPMP/ICH/286/95)
•diabetes mellitus requiring insulin
•surgery in the last 3 months
•severe heart disease
•severe lung diseases
•severe kidney disease
•chronic inflammatory diseases
•endocrine disorders
•diseases that, due to their severity, coupe an assessment of the quality of life limitations caused by fibromyalgia
•schizophrenia, dementia
•severe coagulation disorders
•immunosuppression

发起方

Klinik für Physikalische Medizin und Rehabilitation