Executive Function Training for Binge Eating Disorder and Comorbid Mood/Anxiety Disorders
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 39
- 试验地点
- 2
- 主要终点
- Feasibility as measured by number of treatment sessions attended
研究概览
简要总结
Binge Eating Disorder (BED) is the most common eating disorder, and currently, the best behavioral treatments only work for 40-60% of adults. BED often co-occurs with mood and anxiety disorders, and both are associated with neurocognitive deficits related to executive function (EF). These EF deficits contribute to worsening BED symptoms and make it difficult for these adults to adhere to treatment recommendations. The proposed study aims to develop an EF training enhanced behavioral treatment for BED and compare its effectiveness to the standard cognitive behavioral therapy for patients with BED and a co-occurring mood or anxiety disorder.
详细描述
A randomized controlled trial (RCT) will evaluate an EF training enhanced cognitive behavioral therapy (CBT) for BED (EF-BED+CBT) compared to standard CBT in patients with BED and a comorbid mood/anxiety disorder to assess the feasibility, acceptability, and preliminary efficacy of EF-BED+CBT in reducing binge eating, impairment, and comorbid depression/anxiety symptoms. Adult participants with BED and comorbid mood/anxiety disorder will be randomized to a four month remote treatment of either EF-BED+CBT or CBT alone. Participants will be assessed at baseline, following treatment (month 4) and 2-month follow-up (month 6).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age 18-65
- •Ability to read English at a 6th grade level
- •Clinical or subclinical BED and at least one comorbid mood or anxiety disorder
排除标准
- •Known cognitive disability (e.g., brain injury with loss of consciousness >30 min, intellectual disability)
- •Psychosis
- •Psychiatric condition that could interfere with program participation (e.g., substance abuse, suicide attempt within previous 6 months, active purging, active suicidality)
- •Currently pregnant, lactating or plan to be in the timespan of program follow-up
- •Change in psychotropic medication or other medication that could have impact on weight, binge eating or anxiety/mood symptoms during the previous 3 months
- •Participating in an organized program for overeating
结局指标
主要结局
Feasibility as measured by number of treatment sessions attended
时间窗: Over the course of 4 months of treatment
Attendance at Treatment Sessions
Acceptability
时间窗: At 4 months
Ratings of usefulness of treatment measured by responses to Likert-type ratings developed by the study team.
次要结局
- Binge Eating(Through study completion, an average of 6 months)
- Impairment(Through study completion, an average of 6 months)
研究者
Dawn Eichen
Assistant Adjunct Professor
University of California, San Diego