Role of an Individualized Medical Training in Improving Efficacy and Adherence to a 4-week Treatment With Calcipotriol and Betamethasone Dipropionate Gel for Mild-to-moderate Plaque Psoriasis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 主要终点
- Efficacy as measured by PASI improvement
研究概览
简要总结
The aim of the study will be to evaluate the impact of this individualized practical training on efficacy (evaluated by Psoriasis Area and Severity Index (PASI) and Body Surface Area (BSA) score performed by a physician blinded to the study groups) and adherence (calculated as days wherein gel was applied and as BSA/weight of gel applied rate) to a 4 week long treatment with dovobet gel. On the other hand, the investigators will evaluate in both groups as demographic (as sex, age, job,..) or disease (as severity, duration, impact of quality of life,..) characteristics influence the adherence to the treatment.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Diagnosis of psoriasis will be maid mainly on clinical findings. If doubts, a skin sample will be obtained and evaluated by histopathological examination.
排除标准
- •Patients with palmoplantar, scalp, inverse, erythrodermic, guttate, pustular psoriasis will be excluded.
结局指标
主要结局
Efficacy as measured by PASI improvement
时间窗: 1 month
Efficacy as measured by BSA improvement
时间窗: 1 month
次要结局
- Adherence as measured by days wherein gel was applied(1 month)
- Adherence as measured by BSA/weight of gel applied rate(1 month)
研究者
Giacomo Caldarola
MD, PhD
Catholic University of the Sacred Heart