EUCTR2020-005412-21-BE进行中（未招募）1 期
Effect of dobutamine on hepatic blood flow during goal-directed hemodynamic therapy.
Z Gent0 个研究点目标入组 70 人开始时间: 2021年2月23日最近更新:
适应症
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 70
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •Adult = 18 years = 80 years (female or male).
- •ASA I – II – III.
- •Able to comprehend, sign and date the written informed consent document to participate in the clinical trial.
- •Patient is scheduled for pancreaticoduodenectomy (Whipple`s procedure).
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 25
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range 45
排除标准
- •Allergy to the medication dobutamine.
- •Renal insufficiency (SCr > 2 mg/dL).
- •Severe heart failure (EF < 25%).
- •Hemodynamic unstable patients.
- •Atrial fibrillation.
- •Sinustachycardia > 100 bpm on pre-operative electrocardiogram.
- •BMI > 40.
- •Severe coagulopathy (INR > 2).
- •Thrombocytopenia (< 80 x 103 /mcL).
- •End stage liver disease and/or portal hypertension.
- •Pregnancy and breastfeeding women.
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