CTRI/2024/07/071589尚未招募2 期
To compare and evaluate the effect of dexmedetomedine and fentanyl as adjuvant to intrathecal ropivacaine 0.5 percent heavy in lower limb surgery.
Acharya Vinobha Bhave Rural Hospital1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2024年8月27日最近更新:
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- To evaluate the onset and duration of sensory and motor blockade when Dexmeditomedine and fentanyl used as an adjuvant to ropivacaine 0.5% heavy in lower limb surgeries
研究概览
简要总结
The central nervous system (CNS) comprises the brain and spinal cord. The term neuraxial anesthesia refers to the placement of local anesthetic in or around the CNS. Spinal anesthesia is a neuraxial anesthesia technique in which local anesthetic is placed directly in the intrathecal space. This will be a randomized trial to test the effectiveness of Dexmedetomidine and fentanyl to intrathecal ropivacaine 0.5% heavy in lower limb surgeries.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 50.00 Year(s)（—）
- 性别
- All
入选标准
- •ASA physical status I and II
- •Patient undergoing elective lower limb surgeries, duration of surgery 120-180 minutes
- •Age between 18 to 50 years old
- •Patient giving informed consent.
排除标准
- •Patients with a history of elevated renal parameters, elevated hepatic parameters, heart diseases of ischemic nature, disease related to heart valves, systemic hypertension, history of cancer, sepsis, clotting disturbances and disorders
- •Consumption of narcotics or non steroidal anti inflammatory drugs a day prior to surgery
- •Drug allergy
- •Patients who don’t consent to participate in the study.
结局指标
主要结局
To evaluate the onset and duration of sensory and motor blockade when Dexmeditomedine and fentanyl used as an adjuvant to ropivacaine 0.5% heavy in lower limb surgeries
时间窗: 06 hours
次要结局
- To evaluate the duration of analgesia, hemodynamic stability, side effects
研究者
Akansha Singhal
Acharya Vinobha Bhave Rural Hospital, JNMC
研究点 (1)
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