Impact of Age and Geriatric Co-morbidities on Lymphocyte Phenotype in Patients 70 Years of Age and Older
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 主要终点
- percentage of immune cells in peripheral blood
研究概览
简要总结
An individual's immune profile changes with age, and can sometimes be involved in the development of certain diseases such as infections or cancers, in a process called immunosenescence. Some data tend to show that there is a link between this immune profile and geriatric fragility (autonomy, difficulties with walking, memory, undernutrition, co-morbidities, depression). The aim of this study is to describe this profile, or immune phenotype, and to see if there is a link with the different aspects of geriatric assessment in patients without cancer or infection. In addition, these data will serve as a basis for comparison with the same analyses performed on breast cancer patients at the Centre Georges François Leclerc.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 70 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Person who has not opposed to inclusion in the study
- •Male or female aged 70 and over admitted to the Champmaillot Geriatric Center on an inpatient or outpatient basis.
排除标准
- •Person not affiliated to national health insurance system
- •Person subject to a measure of legal safeguard (curatorship, etc)
- •Person with an acute infection
- •Person with suspected cancer or active cancer
- •Long-term immunosuppressive or corticosteroid therapy
- •HIV and/or HBV and/or HCV positive serology
结局指标
主要结局
percentage of immune cells in peripheral blood
时间窗: At inclusion
technique used: flow cytometry
次要结局
未报告次要终点