NCT00065104已完成2 期
Dehydroepiandrosterone Effects on HIV-1 Replication
National Center for Complementary and Integrative Health (NCCIH)1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2000年10月1日最近更新:
适应症
相关药物
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 1
研究概览
简要总结
This study's purpose is to learn how dehydroepiandrosterone (DHEA) affects the HIV virus, the immune system, hormone levels, body composition and quality of life.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Double
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Evidence of HIV-1 infection
- •HIV RNA <50 copies/mL
- •Stable antiretroviral treatment regimen for at least 8 weeks
- •Age 18 years or older
- •Normal pap smear and mammograph within 1 year (females)
- •Normal prostate-specific antigen level with in one year, age adjusted (males)
排除标准
- •Active opportunistic infections or malignancy other than localized cutaneous KS lesions
- •Concurrent or prior use within the past 8 weeks of DHA, testosterone, other anabolic steroids, corticosteroids, megestrol acetate, growth hormone, IL-2, or thalidomide
- •Diagnosis of AIDS Dementia Complex (stage II or higher)
- •Active substance abuse (e.g., alcohol or injection drugs)
- •Evidence of severe liver dysfunction or hepatic transaminases greater than 3x the upper normal limit
- •Pregnant or breast-feeding
- •History of endocrinologically-responsive tumors (e.g., breast, ovarian, uterine, or prostatic cancer, or malignant melanoma)
研究者
研究点 (1)
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