Retina BioBank: Retina Biomarkers for a Deeper Understanding of Vitreoretinal and Systemic Diseases
试验速览
- 阶段
- 不适用
- 状态
- Enrolling By Invitation
- 发起方
- 入组人数
- 10,000
- 试验地点
- 1
- 主要终点
- To quantify levels of disease state biomarkers implicated in the pathogenesis of various retinal and systemic pathologies
研究概览
简要总结
The RBBK study is a non-interventional, prospective study that will characterize disease state biomarker levels from aqueous humor, vitreous humor, intraoperative tissue and saliva of subjects with various retinal and systemic pathologies.
详细描述
The RBBK study is a non-interventional, prospective study that will characterize disease state biomarker levels from aqueous humor, vitreous humor, intraoperative tissue and saliva of subjects with various retinal and systemic pathologies.
Participants are eligible to be included in the study only if all of the following criteria apply:
- Men or women > 18 years of age
- Subjects with vitreoretinal disease in at least one eye receiving a retinal treatment intervention
- Able and willing to provide signed informed consent
The study will consist of a single visit and a retrospective chart review. The study visit will consist of:
- Screening for eligibility;
- Aqueous humor collection (if applicable);
- Vitreous humor collection (if applicable);
- Intraoperative tissue (if applicable); and
- Saliva collection
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Subjects with vitreoretinal disease in at least one eye receiving a retinal treatment intervention
排除标准
- •Prior intraocular or subtenon steroid injection in the study eye within the prior 1 month of signing informed consent
- •Intraocular or refractive surgery in the study eye within 30 days of signing informed consent
- •Systemic anti-VEGF treatment within 90 days of signing informed consent
结局指标
主要结局
To quantify levels of disease state biomarkers implicated in the pathogenesis of various retinal and systemic pathologies
时间窗: Baseline
An analysis of the ocular fluids and tissues of patients with various vitreoretinal diseases would allow for the development of a deeper understanding of the processes that contribute to their onset and may ultimately provide insight in methods to refine treatment and management options.
次要结局
未报告次要终点