Performances de l'h-FABP Pour Identifier dès Les Urgences Les Embolies Pulmonaires d'évolution défavorable
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 165
- 试验地点
- 2
- 主要终点
- number of death by pulmonary embolism
研究概览
简要总结
The patients presenting with acute pulmonary embolism and right ventricular dysfunction are at high risk for life-threatening events and must be identified in the emergency department for adequate care and hospital admission. Echocardiography can identify right ventricular dysfunction, but this test is not always available, and echocardiographic criteria of right ventricular dysfunction vary among published studies. The primary purpose of this protocol is to study the prognostic value of a cardiac biomarker, h-FABP (heart-type Fatty Acid-Binding Protein) , to identify in the emergency department the patients presenting with high risk pulmonary embolism. As secondary outcomes, H-FABP results will be compared to other cardiac biomarkers (BNP, troponin) and clinical score performances that have been previously studied to stratify the prognosis of patients with pulmonary embolism in the emergency department.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients with acute pulmonary embolism diagnosed in the emergency departement
排除标准
- •patient under guardianship
- •patient without social insurance
- •pregnant women
- •refusal to sign the consent
- •myocardial infarction in the 10 days before pulmonary embolism
结局指标
主要结局
number of death by pulmonary embolism
时间窗: 1 month
life-threatening pulmonary embolism (cardiopulmonary arrest, shock, mechanical ventilation)
时间窗: 1 month
recurrent episode of pulmonary embolism
时间窗: 1 month
次要结局
- prognostic value of a clinical score (PESI), BNP and troponin in acute pulmonary embolism(1 month)
