跳至主要内容
临床试验/CTRI/2022/10/046253
CTRI/2022/10/046253尚未招募2/3 期

To evaluate the effect of Shunti Arka Nebulization and Dhumapana in Tamakashwasa w.s.r to Bronchial Asthma - A comparative clinical study

Dr Amrutha D1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2022年1月11日最近更新:

试验速览

阶段
2/3 期
状态
尚未招募
发起方
入组人数
40
试验地点
1
主要终点
Relief in the symptoms of vegakaleena tamakashwasa

研究概览

简要总结

Tamakashwasa is one such disease of pranavaha strotas caused due to vitiation of vatakapha dosha, producing symptoms like peenasa, ghurghuruka shabda, atiteevravega shwasa, pranaprapeedaka kasa etc. Classics have explained the management with the help of vamana, virechana, dhumapana, sweda and oral medications. On observing the breathing pattern, pathological changes and clinical features, tamakashwasa nearly corresponds with Bronchial asthma.  Tamakashwasa in severe condition is life threatening and needs emergency supportive measures. Acharya chakrapani states tamakashwasa can be treated with dhumapana alone without vamana if a condition is arising out of alpadosha. Acharya sushrutha have also explained dhumapana as one of the pradhanakarma as it does kaphapakarshana in tamakashwasa. Shunti Arka is mentioned as one among the shwasaghna arka and it holds the ushna properties to balance vatakapha dosha. Hence nebulization and dhumapana using shunti is useful to manage mild to moderate symptoms of tamakashwasa with certain modification, can be best alternative method for the management of tamakashwasa.

研究设计

研究类型
Interventional
分配方式
Coin toss, Lottery, toss of dice, shuffling cards etc
盲法
Open Label

入排标准

年龄范围
20.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • 1.Lakshanas of vegakaleena tamakashwasa 2.Signs and symptoms bronchial asthma (mild to moderate condition acc to GINA parameters) 3.20-60 years of age 4.PEF rate: 60-90% 5.Spirometry (FEV): 60-80%.

排除标准

  • <60% 2.Spirometry <60% 3.H/o Cardiac involvement, Cyanosis 4.Any anatomical defect in airway and other complicated Respiratory disorders like TB, Emphysema, Chronic airway limitation •Uncontrolled Diabetes mellitus and Hypertension.

结局指标

主要结局

Relief in the symptoms of vegakaleena tamakashwasa

时间窗: Before treatment - 1st day | After treatment - 5th day | follow up - 12th day

•Kasa with kaphastheevana (cough with expectoration)

时间窗: Before treatment - 1st day | After treatment - 5th day | follow up - 12th day

•Nocturnal waking

时间窗: Before treatment - 1st day | After treatment - 5th day | follow up - 12th day

•Shwasa krichrata (difficulty in breathing)

时间窗: Before treatment - 1st day | After treatment - 5th day | follow up - 12th day

•Ghurghuruka (wheezing)

时间窗: Before treatment - 1st day | After treatment - 5th day | follow up - 12th day

次要结局

  • •PEF(•Spirometry)

研究者

发起方
Dr Amrutha D
申办方类型
Other [self]

研究点 (1)

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