Treatment of Severe Male Infertility - Predictive Factors (Imaging)
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- Functional difference in testicular MRI depending on MD-TESE outcome (=sperm recovery)
研究概览
简要总结
Testes of men with non-obstructive azoospermia (NOA) are imaged using MRI to find potential differences depending on the outcome, ie. sperm recovery in consequent microdissection testicular sperm extraction (MD-TESE).
详细描述
Sperm recovery rate in non-obstructive azoospermia (NOA) men is 43% in Turku University Hospital, depending on the diagnosis leading to NOA. To date, there are no known parameters known to differentiate between successful and unsuccessful sperm recovery.
MRI is performed on men prior to the operation, and the objective is to compare the functional parameters assessed by magnetic resonance imaging between the group of men with positive and the men with negative sperm recovery in testicular microdissection sperm extraction (MD-TESE).
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •non obstructive azospermia
排除标准
- •malignancy
- •contraindication for fertility treatment
结局指标
主要结局
Functional difference in testicular MRI depending on MD-TESE outcome (=sperm recovery)
时间窗: Baseline/ pre-invention
ADC differences by diagnosis and outcome
次要结局
未报告次要终点
研究者
Rauni Klami
MD
Turku University Hospital