Efficacy and safety of Er:YAG laser in comparison with microdermabrasion in facial acne scarring: A randomized clinical trial
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 102
- 试验地点
- 1
- 主要终点
- clinical improvement in facial acne scars between two groups (Microdermabrasion, Er:YAG)
研究概览
简要总结
This study is a randomized controlled, parallel designed, single blinded study comparing the safety and efficacy of two acne scar resurfacing procedures namely microdermabrasion and Er:yag laser. After randomization 52 patients underwent mirodermabrasion and 50 patients underwent Er:YAG laser resurfacing. In each group patients underwent 4-6 sessions of treatment. Patients were followed up at 1 and 6 months after last treatment session. The primary outcome (clinical improvement) was assessed by a blinded dermatologist through photographic comparison before and after treatment. Simultaneously improvement was assessed by investigator (ECCA score) and patients (questionnaire) also. The secondary outcomes assessed were side effects and change in quality of life in partients in each group.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Outcome Assessor Blinded
入排标准
- 年龄范围
- 12.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Adult males or females with atrophic acne scars of grades 2,3 and 4.
排除标准
- •â€¢Age less than 12 years and greater than 60 years.
- •â€¢Pregnant and lactating women.
- •â€¢Active acne.
- •â€¢Coexisting inflammation in adjacent skin secondary to dermatological diseases such as psoriasis, lichen planus, eczemas, acne.
- •â€¢Keloidal tendency.
- •â€¢On isotretinoin for last 6 months to 1 year.
- •â€¢Patients with unrealistic expectations or psychiatric illnesses.
- •â€¢Preexisting bleeding disorder, renal or hepatic diseases.
结局指标
主要结局
clinical improvement in facial acne scars between two groups (Microdermabrasion, Er:YAG)
时间窗: 1 year
次要结局
- side effects, change in quality of life between two groups(1 year)