Utilizing GI: Exploring an Optimum Glycaemic Profile for Cognitive Function Across the Day in Healthy Individuals
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Change in cognitive performance between time points assessed
研究概览
简要总结
This study provides participants with two diets that vary in their glycaemic index values (low vs. high), whilst also measuring cognitive performance and mood.
详细描述
Therefore, the current study introduces cognitive testing into study procedures. Participants will consume the favourable and unfavourable conditions (each containing three meals) on separate days following a crossover, randomised, couterbalanced design. The primary dependent variable is cognitive function, whilst secondary measures include glucose and mood. It is hypothesised that the favourable meal profile will be associated with cognitive and physiological benefits relative to the unfavourable meal profile.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- Single (Participant)
盲法说明
Participants were not told what diet they were consuming each day.
入排标准
- 年龄范围
- 18 Years 至 25 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Aged between 18 and 25 years of age
- •Willing to participate in the entire study (signed informed consent required)
- •Male or female (not pregnant)
排除标准
- •Suffer from diabetes
- •Are anaemic
- •Have any food intolerances or allergies
- •History of alcohol or drug misuse
- •Diagnosed with any of the following;
- •High blood cholesterol
- •High blood pressure
- •Thyroid disorder
- •Heart problems, stroke or any vascular disease in the past 12 months
- •Inflammatory diseases such as rheumatoid arthritis
- •Bone related conditions, such as osteoporosis
- •Renal, gastrointestinal, respiratory, liver disease or cancer
- •You are presently taking part in another clinical trial or research study
- •You are an elite athlete (very high intensity training more than 3 times a week)
- •You are currently on a specific diet, and are unwilling to cease during the testing period
- •You are intending to regularly use medication which affects gastrointestinal motility
研究组 & 干预措施
Low GI diet
This diet contained three Low GI meals. This was the Low Glycaemic Diet intervention.
干预措施: Low Glycaemic Diet (Dietary Supplement)
High GI diet
This diet contained three meals, all with a high GI value. This was the High Glycaemic Diet intervention.
干预措施: High Glycaemic Diet (Dietary Supplement)
结局指标
主要结局
Change in cognitive performance between time points assessed
时间窗: This was tested 9 times a day, with two days, giving a total of 18 times. Each battery of four tasks lasted approximately 15 minutes
A participants performance over four cognitive tasks
次要结局
- Glycaemic profile(This was measured 23 times a day, for two days, giving a total of 46 times)
- Sleepiness(This takes approximately 30 seconds to complete. Participants were tested six times a day. There were two test days. Giving a total of 12 times, or approximately 6 minutes overall.)
- Fullness(This takes approximately 30 seconds to complete. Participants were tested six times a day. There were two test days. Giving a total of 12 times, or approximately 6 minutes overall.)
- Mood (alertness, anxiety and contentment) using the Bond-Lader (1974) Visual Analogue Scale(This takes approximately 5 minutes to complete. Participants were tested six times a day. There were two test days. Giving a total of 12 times, or approximately 60 minutes of mood scale completion.)
- Hunger(This takes approximately 30 seconds to complete. Participants were tested six times a day. There were two test days. Giving a total of 12 times, or approximately 6 minutes overall.)
研究者
Matthew Grout
Doctoral Researcher
University of Reading