Analysis of the Effect of a Tool-Handling Intervention in a Specific Context on the Linguistic Processing of Healthy Young Adults
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Assessment of Synthatic Processing Performance - Reaction time
研究概览
简要总结
This randomized controlled trial aims to investigate the effects of a context-specific tool-handling intervention on linguistic processing in healthy young adults. Participants will be allocated into three groups: a dexterous tool-use training group, a dexterous manual training group without tools, and a Control group.
The dexterous tool-use training group will perform a task-oriented activity involving the use of tweezers to place colored beads into a mandala within a specific functional context. The intervention requires sequential motor planning, force control, precision, and goal-directed tool use. The dexterous manual training group without tools will perform a similar bead-placement activity without tool use, involving direct hand manipulation and lower task complexity. Both intervention groups will participate in synchronous online sessions via Google Meet for 20 minutes per day, five times per week, over a two-week period.
The Control group will not receive any structured intervention and will instead be instructed to perform one activity of daily living using the non-dominant upper limb once per day during the two-week period.
Linguistic processing will be assessed through a sentence judgment task involving sentences with and without semantic violations, in which participants will classify the sentences as correct or incorrect while electroencephalographic activity (EEG) is recorded. Additionally, sleep quality and manual dexterity will also be evaluated.
The findings of this study may contribute to understanding the relationship between tool-related motor training and linguistic processing, particularly the interaction between motor and language systems in healthy young adults. Additionally, the study may provide evidence regarding neurophysiological changes associated with context-specific motor interventions.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 19 Years 至 24 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy young adults aged between 19 and 24 years;
- •Right-handed individuals.
排除标准
- •Previous diagnosis of neurological and/or psychiatric disorders;
- •History of traumatic brain injury;
- •Use of psychoactive substances or medications that may affect cognitive functioning;
- •Pregnancy or suspected pregnancy.
结局指标
主要结局
Assessment of Synthatic Processing Performance - Reaction time
时间窗: Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
Linguistic processing will be evaluated through a computerized sentence judgment task composed of 60 sentences containing grammatical agreement violations and control sentences. Reaction time will be measured as the time elapsed between the presentation of each sentence and the participant's button press indicating whether the sentence is grammatically correct or incorrect. Mean reaction time across trials will be reported in milliseconds (ms).
Assessment of Synthatic Processing Performance - Accuracy
时间窗: Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion)
Linguistic processing will be evaluated through a computerized sentence judgment task composed of 60 sentences containing grammatical agreement violations and control sentences. Accuracy will be assessed as the absolute number of correct responses. The absolute number of incorrect responses (errors) will also be recorded.
次要结局
- N200 Event-Related Potential Mean Amplitude(Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion))
- P300 Event-Related Potential Mean Amplitude(Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion))
- N200 Event-Related Potential Peak Latency(Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion))
- P300 Event-Related Potential Peak latency(Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion))
- Assessment of Syntactic Production - Hierarchical Embedding in Spontaneous Discourse(Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion))
- Assessment of Syntactic Production - Clauses per Sentence in Spontaneous Discourse(Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion))
- Assessment of Syntactic Production - Left-Branching Load (Frazier Index) in Spontaneous Discourse(Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion))
- Manual dexterity(Change from PRE assessment (up to 1 week before intervention) to POST assessment (up to 1 week after intervention completion))
研究者
Aline de Souza Pagnussat
Principal Investigator
Federal University of Health Science of Porto Alegre