The effect of two dosages of theobromine and caffeine on mood and cognition in healthy subjects - 08063V theobromine and caffeine

nilever0 个研究点目标入组 28 人开始时间: 待定最近更新: 2024年5月6日

适应症

试验速览

暂无简介。

•Age at start of the study >= 18 and <= 55 years
•Being female
•Body mass index (BMI) >= 18.5 and <= 30.0 kg/m2.
•Reported alcohol consumption < 14 alcohol units/week
•Agreeing to be informed about medically relevant personal test-results
•Informed consent signed
•Willing to refrain from caffeine and theobromine for 28 hours, from 8 p.m. on the day prior to the measurement day until the end of the measurement day (0:00 - midnight)
•Apparently healthy: no reported current or previous diseases or disorders which might effect study measurements assessed by Research physician
•Consuming animal foods products (gelatine).
•Consumes dark chocolate at least once in a month
•Having a general practitioner (GP)

•Being an Unilever employee
•Consumes more than 250 mg caffeine daily
•Using or planning to use any medically prescribed diet or weight-loss diet or making any attempt to control diet at screening and during the entire study.
•Reported intense sporting activities > 10 h/w
•Subjects who undergoing medical treatment that may interfere with the study outcome.
•Use of systemic antibiotics in the period of 3 months prior to the study
•Reported participation in another biomedical study 1 month before the start or during the study.
•Reported intolerance or allergy for one of test products or standardized meal
•The habit of smoking during the past half year or using nicotine containing medicines during the past month
•Reported lactating (or lactating < 6 weeks ago), pregnant (or pregnant < 3 months ago) or wish to become pregnant during the study
•Office systolic blood pressure > 160 mmHg and/ or diastolic blood pressure > 95 mmHg, irregular heart rate and/or heart rate > 100 bpm. Eligibility of subjects with a heart rate <56 bpm will be assessed by the research physician
•Not able to perform the computer tasks assessed during screening
•Reported participation in night shift work during the study period

发起方

nilever