A randomised controlled trial and economic evaluation of a community-based physical activity intervention to prevent mobility-related disability for retired older people: the REACT (REtirement in ACTion) trial
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 777
研究概览
简要总结
2018 Protocol article in https://www.ncbi.nlm.nih.gov/pubmed/29665854 protocol 2022 Results article in https://doi.org/10.1016/S2468-2667(22)00004-4 (added 22/03/2022) 2022 Results article in https://doi.org/10.1016/S2468-2667(22)00030-5 Cost-effectiveness (added 22/03/2022) 2023 Results article in https://doi.org/10.1186/s12966-023-01434-0 Qualitative results (added 27/04/2023) 2023 Other publications in https://pubmed.ncbi.nlm.nih.gov/37299849/ Validation of the pfSTEP digital biomarker (added 11/07/2024) 2021 Results article in https://pubmed.ncbi.nlm.nih.gov/35361556/ MRI sub study results (added 11/07/2024) 2022 Results article in https://pubmed.ncbi.nlm.nih.gov/35658857/ delivery fidelity of the intervention part of the process eveluation (added 11/07/2024) 2023 Results article in https://pubmed.ncbi.nlm.nih.gov/37575112/ long-term functionality (added 11/07/2024)
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Retired men and women aged 65 or older
- •2. Plan to reside in the target area (Bath/Bristol, Devon, Birmingham) for at least 24 months
- •3. Score 48 (inclusive) on the Short Physical Performance Battery (SPPB)
排除标准
- •1. A documented or patient reported medical condition that would preclude participation, including:
- •1.1. Arthritis so severe it would prevent participation in physical activity
- •1.2. Parkinson’s disease
- •1.3. Dementia
- •1.4. Lung disease requiring use of corticosteroids or supplemental oxygen
- •1.5. Severe kidney disease that requires dialysis
- •1.6. Severe heart disease that would prevent participation in physical activity (for example chest pain when walking one or two hundred yards or up a flight of stairs)
- •1.7. An implanted cardiac defibrillator, a cardiac arrest which required resuscitation
- •1.8. Severe uncontrolled psychiatric illness
- •1.9. Currently receiving radiation therapy or chemotherapy treatment for cancer
- •1.10. Awaiting knee or hip surgery
- •1.11. Major heart surgery (including valve replacement or bypass surgery) or spinal surgery in the last six months
- •1.12. Any other clinical condition that their GP or clinician considers would make them unsuitable for participation in a physical activity rehabilitation programme to prevent decline of lower limb functioning
- •2. Self-reported inability to walk across a room or the need for a walker or the help of another person
- •3. Existing major mobility limitation.
- •4. Being unable to complete the 4m walk component of SPPB
- •5. Current involvement in other regular (at least weekly) exercise programmes that aim to build lower limb capacity or fitness (e.g. walking programmes)
- •6. Living in residential or nursing care
- •7. Another member of the household participating in REACT