Assesment of Postoperative Analgesic Efficacy of Preoperatively Applied Genicular Block on Total Knee Arthroplasty: A Randomized Controlled Study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 44
- 主要终点
- Visual Analog Scale Measure
研究概览
简要总结
The aim of this study is to investigate the postoperative pain relieving effect of preoperative genicular block in total knee arthroplasty surgery. The main questions it aims to answer are:
- Do visual analog scale (VAS) scores decrease in patients who underwent geniculate block?
- Does opioid consumption decrease in patients who underwent geniculate block?
Researchers will compare postoperative pain in patients who received genicular block with those who did not.One group of patients will be administered 0.25% bupivacaine with the geniculate block method. The other group will not undergo any intervention. Both groups will be administered intravenous morphine for postoperative analgesia.
详细描述
Patients scheduled for knee arthroplasty will be randomly assigned into two groups. One group will receive a genicular nerve block prior to surgery , while the other group will not undergo any interventional procedure. The genicular nerve block will be administered in three quadrants around the knee, with each injection consisting of 5 mL of 0.25% Marcaine. All injections will be performed by investigator MA. Patient assessments will be conducted by investigator MO. Postoperative intravenous analgesia will be provided to both groups.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Double (Care Provider, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Scheduled for unilateral and primary total knee arthroplasty
- •Older than 18 years of age
排除标准
- •Younger than 18 years
- •Bilateral knee arthroplasty
- •Revision case of knee arthroplasty
研究组 & 干预措施
Genicular block group
this group consists of the patients receiving genicular block preoperatively and they will be given morfin with PCA (Patient controlled analgesia) and paracetamol 3x1000 mg intravenous and diclofenac 75 mg intramuscular (if needed)
干预措施: Genicular blocks (bupivakain) (Drug)
Genicular block group
this group consists of the patients receiving genicular block preoperatively and they will be given morfin with PCA (Patient controlled analgesia) and paracetamol 3x1000 mg intravenous and diclofenac 75 mg intramuscular (if needed)
干预措施: Patient Control Analgesia (PCA) Morphine group (Drug)
patients only given PCA-morfin postoperatively
this group consists of the patients given morfin with PCA, paracetamol 3x1000 mg and diclofenac (if needed)
干预措施: Paracetamol (acetaminophen) + Diclofenac Sodium (Drug)
Genicular block group
this group consists of the patients receiving genicular block preoperatively and they will be given morfin with PCA (Patient controlled analgesia) and paracetamol 3x1000 mg intravenous and diclofenac 75 mg intramuscular (if needed)
干预措施: Paracetamol (acetaminophen) + Diclofenac Sodium (Drug)
patients only given PCA-morfin postoperatively
this group consists of the patients given morfin with PCA, paracetamol 3x1000 mg and diclofenac (if needed)
干预措施: Patient Control Analgesia (PCA) Morphine group (Drug)
结局指标
主要结局
Visual Analog Scale Measure
时间窗: 0-48 hours
VAS scores are assessed at 0th, 24th and 48th hours post operatively VAS score consists of 0-10 in numbers, the bigger the number the worse the pain
opioid consumption
时间窗: 0-48 hours
Morphine consumption is assesed by PCA
次要结局
未报告次要终点
研究者
Mustafa Azizoğlu
Associated Professor
Mersin University