Light Exposure Tracker in Alzheimer's Disease.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Saliva samples for melatonin levels
研究概览
简要总结
The purpose of this research study is to investigate the relationship between reminder messages sent via text and compliance with a daily morning light intervention designed to advance the circadian clock. Twenty healthy adults will be recruited to participate in a randomized, cross-over study where daily messages are, or are not, provided to remind participants to carry out the intervention.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 55 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •healthy adults over the age of 55
- •score of 25 or greater on MoCA
排除标准
- •Severe sleep apnea
- •restless leg syndrome
- •obstructing cataracts
- •macular degeneration
- •diabetic retinopathy
- •use of sleep medications
- •brain disease
研究组 & 干预措施
Light Googles plus reminder text messages
Participants use green light goggles for one hour each morning for two consecutive weeks and also receive a daily text message reminding them to wear the light goggles
干预措施: Light goggles (Device)
Light Googles plus reminder text messages
Participants use green light goggles for one hour each morning for two consecutive weeks and also receive a daily text message reminding them to wear the light goggles
干预措施: Daily reminder test message (Behavioral)
Light Goggles alone
Participants use green light goggles for one hour each morning for two consecutive weeks
干预措施: Light goggles (Device)
结局指标
主要结局
Saliva samples for melatonin levels
时间窗: Baseline and 2-weeks post-intervention for each Arm
Serial saliva samples will be collected to calculate dim light melatonin onset.
次要结局
- Light exposure using the Speck(worn all 12 study weeks)
- Sleep time using actigraphy(worn all 12 study weeks)
研究者
Mariana Figueiro
Professor
Icahn School of Medicine at Mount Sinai