Pilot Study: Collection of Urine From Sanitary Napkins for the Analysis of Micronutrient Deficiencies
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Correlation untreated and expressed urine
研究概览
简要总结
This study aims to find an easy urinary collection method for the assessment of urinary markers of micronutrient status.
详细描述
Urinary collection in newborns and infants can be difficult. Our study aims to find an easy and cheap alternative to urinary collection bags and specialized pads that can be used to measure biomarkers of iodine and vitamin B12 status in urine and can be employed in large scale trials. Using correlation analyses, the association of urinary iodine and methylmalonic acid from healthy volunteers will be assessed between untreated sample and a sample expressed from a sanitary napkin. Participants will be recruited based on their dietary pattern (omnivorous, vegetarian and vegans) to have a broad spectrum of analyte concentration. Participants weight, height, age, nutritional supplement use and diet will be assessed.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 40 Years(Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy volunteers Written informed consent
排除标准
- •BMI < 18,5 and >24,9 Use of medication (except contraceptives) Smoking
结局指标
主要结局
Correlation untreated and expressed urine
时间窗: 8-9 weeks after completion
Correlation of creatinine, methylmalonic acid and iodine between unprocessed urine and urine expressed from a sanitary diaper to evaluate possible matrix effects on analytes.
次要结局
- Correlation of urinary biomarkers with food and supplement intake(8-9 weeks after completion)
研究者
Maren Podszun
Dr. rer. nat. Maren Podszun
University of Hohenheim
