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临床试验/NCT05777356
NCT05777356已完成不适用

Pilot Study: Collection of Urine From Sanitary Napkins for the Analysis of Micronutrient Deficiencies

University of Hohenheim1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2023年3月8日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
30
试验地点
1
主要终点
Correlation untreated and expressed urine

研究概览

简要总结

This study aims to find an easy urinary collection method for the assessment of urinary markers of micronutrient status.

详细描述

Urinary collection in newborns and infants can be difficult. Our study aims to find an easy and cheap alternative to urinary collection bags and specialized pads that can be used to measure biomarkers of iodine and vitamin B12 status in urine and can be employed in large scale trials. Using correlation analyses, the association of urinary iodine and methylmalonic acid from healthy volunteers will be assessed between untreated sample and a sample expressed from a sanitary napkin. Participants will be recruited based on their dietary pattern (omnivorous, vegetarian and vegans) to have a broad spectrum of analyte concentration. Participants weight, height, age, nutritional supplement use and diet will be assessed.

研究设计

研究类型
Observational
观察模型
Other
时间视角
Prospective

入排标准

年龄范围
18 Years 至 40 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Healthy volunteers Written informed consent

排除标准

  • BMI < 18,5 and >24,9 Use of medication (except contraceptives) Smoking

结局指标

主要结局

Correlation untreated and expressed urine

时间窗: 8-9 weeks after completion

Correlation of creatinine, methylmalonic acid and iodine between unprocessed urine and urine expressed from a sanitary diaper to evaluate possible matrix effects on analytes.

次要结局

  • Correlation of urinary biomarkers with food and supplement intake(8-9 weeks after completion)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Maren Podszun

Dr. rer. nat. Maren Podszun

University of Hohenheim

研究点 (1)

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