DEVELOPMENT AND VALIDATION OF A PROGNOSTIC SCORE FOR PREDICTING OUTCOMES IN PATIENTS UNDERGOING LIVING DONOR LIVER TRANSPLANTATION

Liver transplantation is a viable treatment option for patients with end stage liver disease, hepatocellular carcinoma, fulminant hepatitis. The outcome of liver transplant has been improved in later days due to advancements in surgical techniques , immunosuppression , enhanced knowledge in managing the allograft recipient.

Despite the multiple options , there is no agreement on the best scoring system to predict outcomes after liver transplant.The presently used scores have poor sensitivity and specificity in predicting the outcomes after the surgery.

The anaesthesia and surgical factors play a very important role in predicting the outcome of surgery. The outcome after surgery also predominantly depends upon the disease severity, patient factors. None of the previous scores have included patient factors like sarcopenia, MELD-Na and anaesthesia & surgical factors (fluid requirement including blood transfusion, inotropic support, cold ischemia time ,warm ischemia time, GRWR ) into a simple single score. So we aimed to consolidate all these factors into a new scoring system .

Hence, the aim of the present study is to develop a novel scoring system to predict the outcome after the LDLT.