Association Between COVID-19 Vaccination and Reduced Mortality in Nursing Home Facilities.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 258
- 试验地点
- 1
- 主要终点
- Cause of death
研究概览
简要总结
To describe the effect on mortality in nursing home facilities during three separate equally long periods during the pandemic and more specifically to analyse the effect on mortality of improved preventive routines and vaccination.
详细描述
Retrospective descriptive cohort study in Östergötland County Council, Sweden comprising 136 nursing home facilities with a possibility to host 4500 residents. All residents in any of these NHs who had a laboratory confirmed COVID-19 diagnosis between March 2020 to April 2021 and who died within 30 days after the verified diagnosis are included. The study is undertaken as a retrospective record review. From the records patient-level data on demographic variables, clinical signs, comorbidity, performance status, and cause of death are collected.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All residents in any of 136 nursing homes in Östergötland County Council, Sweden who had a laboratory confirmed COVID-19 diagnosis and who died within 30 days after the verified COVID-19 were included in three separate periods: First period from March 31 to June 30 2020; second period from October 15 2020 to January 15 2021; third period from January 16 to April 18 2021.
排除标准
- 未提供
结局指标
主要结局
Cause of death
时间窗: March 2020 to April 2021
assessment of cause of death
Frailty
时间窗: March 2020 to April 2021
The combined assessment of performance status and frailty was adapted to the record review method
Comorbidity
时间窗: March 2020 to April 2021
Number of diagnoses bedisde COVID-19
次要结局
未报告次要终点
研究者
Lena Nilsson
MD, Associate Professor, Chief Medical Officer
University Hospital, Linkoeping