The Copmparison of Accuracy of PtcCO2 and in PetCO2 in COPD Patients
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- concordance between the values of PetCO2 and PaCO2 measured at the same time
研究概览
简要总结
The pathophysiological characteristics of COPD is irreversible airflow restriction which may influence the gas exchange and cause the abnormal PaO2 and PaCO2. Assessment of the partial arterial pressure of carbon dioxide (PaCO2 ) is the 'gold standard' for the evaluation of the adequacy of alveolar ventilation.Method used mostly nowadays : arterial puncture which is accurate but is invasive 、painful、 non-dynamic and there is risk of infection and tissue、nerve damage. Noninvasive measurement methods (Most commonly used)： end-tidal CO2（ ETCO2）、 transcutaneous CO2(TcCO2). They all can monitor the PaCO2 dynamically、 noninvasively, but is existence of controversy of the accuracy. So the investigators want to compare the accuracy of these two noninvasive methods for assessment of PaCO2.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 20 Years 至 100 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •COPD patients
排除标准
- •hemodynamics is unstable;
- •any other lung disease despite COPD；
- •other diseases influencing experiments: Cognitive impairment disease、 mouth and nose trauma.
结局指标
主要结局
concordance between the values of PetCO2 and PaCO2 measured at the same time
时间窗: 1 hour
concordance between the values of PetCO2 and PaCO2 measured at the same time
concordance between the values of PtcO2 and PaCO2 measured at the same time
时间窗: 1 hour
concordance between the values of PtcO2 and PaCO2 measured at the same time
次要结局
未报告次要终点
研究者
Shanshan Zha
doctor
The First Affiliated Hospital of Guangzhou Medical University