Predictors of Mortality Among Ventilator Associated Pneumonia Patients
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 140
- 主要终点
- Mortality rate at 28 days.
研究概览
简要总结
In this context, this study aims to explore the risk factors for mortality from VAP in respiratory ICU.
详细描述
Pneumonia is the most common infection treated within ICUs and carries significant mortality risk . Ventilator-associated pneumonia (VAP) is a specific form of nosocomial pneumonia occurring in patients greater than 48 hours after intubation and the initiation of mechanical ventilation .
VAP is considered a leading cause of morbidity and mortality among intensive care unit infections. Despite various preventive measures, the incidence of VAP remains high .
In studies, VAP-related mortality is 14-70% . It is contemplated that there are independent risk factors, increasing VAP-related mortality .
However, the question of which factors are associated with early or late mortality in patients with VAP diagnosis, remains unanswered. Early identification and understanding of the etiology of VAP in the ICU is essential to prevent mortality and morbidity.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •This study will enroll:
- •adult participants over 18 years old who had undergone mechanical ventilation for longer than 48 hours.
- •Only the first episode of VAP for each patient will be included.
排除标准
- •Patients who are less than 18 years old.
- •Pneumonia diagnosed before mechanical ventilation.
结局指标
主要结局
Mortality rate at 28 days.
时间窗: 28 days
Evaluation of number of dead patients from vap wihin 28 days of infection and
Percentage of risk factors of VAP mortality.
时间窗: 28 days
Search for risk factors for mortality of vap wihin 28 days of infection.
次要结局
未报告次要终点
研究者
Marwa Hussien kilany
principal investigator
Assiut University