NCT01001273Unknown不适用
Hyperinsulinemic Normoglycemic Clamp for Pancreas and Simultaneous Pancreas/Kidney Transplant Recipients
McGill University Health Centre/Research Institute of the McGill University Health Centre2 个研究点 分布在 1 个国家目标入组 80 人开始时间: 2010年4月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 80
- 试验地点
- 2
- 主要终点
- The number of post-transplants all complications up to 30 days (Clavien grading).
研究概览
简要总结
This study proposes a simple and safe way of lowering this complicate rate, while improving graft recovering and protecting the graft as it recovers from the transplant. The investigators hypothesize that by maintaining a tight glucose control via a glucose-insulin clamp during surgery and 72 hours post-operatively the investigators will be able to lower the complication rate by 50%.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Male or female patient over 18 years of age
- •Patient is about to receive a pancreas or a simultaneous pancreas/kidney transplant
- •Able to give written informed consent prior to any study specific procedure
排除标准
- •Multi-organ transplant other than kidney transplant
- •No central venous access available to deliver the D20W solution
结局指标
主要结局
The number of post-transplants all complications up to 30 days (Clavien grading).
时间窗: 30 days post-operative
次要结局
- The number of 30 days post-transplant serious medical complication (Clavien grade 3, 4)(30 days post-op)
- The length of hospital stay (days)(Length of hospital stay (day 1 until discharge))
研究者
研究点 (2)
Loading locations...
相似试验
已完成
不适用
Use of a Hyperinsulinemic-hypyglycemic Clamp to Study Hypoglycemia: a Method Development StudyDiabetesNCT03839511Pennington Biomedical Research Center4
撤回
不适用
A Comparison of Strict Glucose Control With Usual Care at the Time of Islet Cell TransplantationIslet TransplantationDiabetes Mellitus, Type 1NCT01123122Vancouver Coastal Health
已完成
2 期
The role of insulin therapy in reducing critical illness polyneuropathy and myopathy in pediatric intensive care unitpolyneuropathy and myopathy.Diabetic polyneuropathyE10,E11.E1IRCT201108117295N1Vice chancellor for research, Tabriz University of Medical Sciences30
已完成
不适用
The Effect of the Hyperinsulinemic Normoglycemic Clamp on Myocardial Function and Utilization of GlucoseAortic Valve ReplacementCardiac SurgeryHyperglycemiaAortic StenosisNCT01187329The Cleveland Clinic100
已完成
不适用
Dual-hormone Artificial Pancreas Versus Single-hormone Under Exercise and a Meal ChallengeType 1 DiabetesNCT06082973Universitat Politècnica de València15