Comparative Study of the Effects of Green Tea and Peppermint Herbal Mouthwash on Halitosis.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 88
- 主要终点
- evaluation of changes in organoleptic score
研究概览
简要总结
Background:
Herbal remedies can have the role of prevention and control of bad breath Since in the previous studies, therapeutic and antibacterial effect of green tea and peppermint had been proven .we studied and compared the effects of green tea and peppermint mouthwashes on halitosis.
Materials and Methods:
This single-blind clinical trial study with cross over design total of 88 volunteer dental students who complained bad breath and had organoleptic score (>= 2) and higher average test scores were enrolled. The students were divided randomly into two groups Green Tea - Peppermint were assigned. Organoleptic test in the baseline, on the 7 day, 14 and 21 measured after rinsing the mouthwashes .As well as the satisfaction of both plants on the last day was considered. Data analysis was performed using tests; Wilcoxon signed rank test, Mann Whithney u, GEE (Generalized Estimating Equation -ordinal logistic regression).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Supportive Care
- 盲法
- Double (Investigator, Outcomes Assessor)
盲法说明
investigator
入排标准
- 年龄范围
- 18 Years 至 30 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •organoleptic number equal to or higher 2 no foods (garlic and onion) 48 hours before organoleptic test
排除标准
- •systemic disease
- •use of antibiotics during study use of other mouthwash during study
结局指标
主要结局
evaluation of changes in organoleptic score
时间窗: baseline,7 days,14 days,21 days
0-5 organoleptic scale
次要结局
- satisfaction of patients(21 days)
研究者
Mahin Bakhshi
Associate Professor of Oral Medicine
Shahid Beheshti University of Medical Sciences