The Performance of Renal Doppler Ultrasound in Predicting Outcome of Dialysis Weaning
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 33
- 试验地点
- 1
- 主要终点
- Dialysis weaning
研究概览
简要总结
Acute kidney injury (AKI) is a frequent problem in the intensive care unit (ICU) affecting more than 50 % of patients. AKI is associated with several adverse outcomes, including increased mortality and increased length of ICU- and hospital stay, in particular in patients requiring Renal Replacement Therapy (RRT).
Choosing the optimal time for attempting liberation from RRT is still unclear. With this study, we will describe the ability of renal ultrasound in predicting the outcome of dialysis weaning.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All patients ≥ 18 years admitted to the ICU, Aarhus University Hospital who are treated with dialysis as continuous renal placement therapy (CRRT) and planned to undergo dialysis weaning
排除标准
- •Insufficient ultrasonographic imaging of the kidneys
- •Known morphological kidney disease
- •Previous need of chronic RRT
- •Prior participation in the study
- •Need of extracorporeal membrane oxygenation (ECMO) or other heart assist device
结局指标
主要结局
Dialysis weaning
时间窗: 7 days
If discontinuation of Dialysis is successful or not. Successful dialysis weaning is defined as no renal replacement therapy (RRT) required within the first 7 days after stopping continuous renal replacement therapy (CRRT) and non-successful weaning as the need for RRT within the first 7 days.
次要结局
- Renal Doppler arterial Resistive Index (RI)(Measured at the beginning of weaning and after 6 hours.)
- Renal Doppler Venous Impedance Index (VII)(Measured at the beginning of weaning and after 6 hours.)
- Portal vein Doppler Pulsatility Fraction PF)(Measured at the beginning of weaning and after 6 hours.)
- Urine Output(4 days)
- Renal Doppler Renal Venous Stasis Index (RVSI)(Measured at the beginning of weaning and after 6 hours.)
- Urine Creatinine Clearance(4 days)
研究者
Johan Fridolf Hermansen
Principal Investigator
Aarhus University Hospital