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临床试验/NCT03678519
NCT03678519Unknown不适用

Occupational Health Hazards Among Flour Mills Workers And Smoking Situation Analysis Among Smokers, Assiut

Assiut University1 个研究点 分布在 1 个国家目标入组 200 人开始时间: 2020年9月最近更新:
适应症

试验速览

阶段
不适用
入组人数
200
试验地点
1
主要终点
Detect number of workers who have occupational diseases

研究概览

简要总结

Flour milling is from the oldest trade industry. Several problems arise during functioning and maintenance operations. Production process involves the breakdown of grains to separate their outer covering and inner endosperm grinding to fine flour particles. Workers are at substantial risk with two main problems causing severe health issues and accidents. The first is the improper flour milling process including intake and final products collection systems. The second is the unawareness and unavailability of PPE.

详细描述

Flour is a complex organic dust consisting of one or a mixture of several cereal grains (wheat, rye, millet, barley, oats or corn cereal) that have been processed or ground by milling. In addition, flour may contain a diverse number of contaminants, such as silica, fungi and their metabolites (mycotoxins), bacterial endotoxins, insects, mites, mammalian debris and chemical additives such as pesticides and herbicides. Occupational exposure to flour dust occurs in different settings, as: bakeries, grain mills and flour mills.

Many industries, including flour mills, generate dust, which is released into air, then inhaled during industrial processes as: cleaning, packaging and shipping. Occupational respiratory diseases are usually caused by extended exposure to irritating or toxic substances that may cause acute or chronic respiratory diseases.

It has long been known that occupational exposure to flour dust may cause respiratory illness, ranging from simple irritation to rhinitis and asthma, due to components of the grains themselves as well as contaminants of the flour dust and additives.

Flour mills workers have been in an environment exposed to flour dust, suffering from sensitization, occupational asthma, allergic rhinitis, obstructive lung diseases and eye infection.

Mill workers' suffer from conjunctivitis, allergic and baker's asthma, wheezing, febrile reactions, grain fever, lung fibrosis, rhinitis, allergic alveolitis, impairment of lung function and chronic obstructive pulmonary disease. These respiratory symptoms with continuing occupational exposure can lead to worker disability that force them to leave their jobs.

研究设计

研究类型
Observational
观察模型
Other
时间视角
Cross Sectional

入排标准

年龄范围
18 Years 至 60 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • 未提供

排除标准

  • 未提供

结局指标

主要结局

Detect number of workers who have occupational diseases

时间窗: 6 months

次要结局

  • Number of patients who have declined pulmonary function tests(6 months)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Ayah Atef Alkarn

Principal investigator

Assiut University

研究点 (1)

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