NCT01125150已完成不适用
Spectroscopic and Colorimetric Analysis of Acanthosis Nigricans in Patients With Hyperinsulinemia
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 9
- 试验地点
- 1
研究概览
简要总结
Acanthosis Nigricans is skin disease that associated with hyperinsulinemia. Clinical is velvety hyperpigmented plaques on neck, axilla, groin. If hyperinsulinemia is improved by treated with oral metformin and/ or diet control, acanthosis nigricans would be improved as well. Hyperpigmented plaques will be changed. We assess objective measurement by using spectroscopic and colorimetric analysis.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 11 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Subjects must have an elevated fasting insulin level, suggesting they are in an insulin resistant state.
- •Subjects must carry a diagnosis of acanthosis nigricans, which will be verified by a Dermatologist before entry into the study. If necessary, a small 4mm punch biopsy may be taken to document dermatopathology consistent with acanthosis nigricans.
- •Subjects must be willing and able to undergo treatment with Metformin, including initial referral and follow up.
- •Agree to abide by the investigator's guidelines
- •Be able to understand the requirements of the study, the risks involved and are able to sign the informed consent form
- •Agree to follow and undergo all study-related procedures
排除标准
- •Subjects with Type 1 Diabetes are excluded because of their naturally insulin-deficient, rather than hyper-insulinemic, states.
- •Women who are lactating, pregnant, or planning to become pregnant.
- •Any reason the investigator feels the patient should not participate in the study.
研究者
Iltefat Hamzavi
Dermatologist
Henry Ford Health System
研究点 (1)
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