EUCTR2008-002578-36-FR进行中（未招募）1 期
Etude d’efficacité et d’acceptabilité d’un traitement cholinergique dans l’apathie parkinsonienne Cholinergic treatment in Parkinsonian Apathy: ChoPA - I” - ChoPA-I
CHRU de LILLE0 个研究点目标入组 29 人开始时间: 2008年7月21日最近更新:
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 29
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •Parkinson dieases since 5 years
- •MMSE score =27
- •Matis score =130
- •No dementia and depression (defined by the DSM-IV)
- •MADRS score < 18
- •IF subthalamic stimulation there are more critria
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range
排除标准
- •more 80 years old
- •dopaminergic treatment
- •Treatment by High frequency stimulation of subthalamic nuclei
- •resting tremor very severe and uncontrolled
- •psychosis dopaminergic
- •Hypersensitivity to cholinesterase ihnibitor
- •Important cardivascular disorder
- •hepatic insufficiency
- •Evolutionary gastro-duodenal ulcer
- •undernutrited
- •Grave pathology
- •pregnancy and feeding
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