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临床试验/NCT07719192
NCT07719192尚未招募不适用

Effects of Alternate Nostril Breathing and Bellows Breath on Sputum Clearance, Pulmonary Function Test and Quality of Life Among COPD Patients

Riphah International University1 个研究点 分布在 1 个国家目标入组 54 人开始时间: 2026年6月1日最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
入组人数
54
试验地点
1
主要终点
Forced Vital Capacity

研究概览

简要总结

COPD is a common respiratory disease characterized by progressive airflow obstruction, dyspnea, chronic cough, and sputum production. Alternate nostril breathing and bellows breath are pranayama-based breathing techniques that may improve respiratory function and overall well-being. This randomized clinical trial aims to compare the effects of these techniques on sputum clearance, pulmonary function tests, and quality of life in COPD patients. The study will be conducted at Punjab Institute of Cardiology using convenient sampling. Participants will be divided into two groups: Group A will perform alternate nostril breathing, while Group B will perform bellows breath exercises for 15-20 minutes daily over 3-4 weeks. Outcome measures include sputum clearance, spirometry, and quality of life questionnaires. Data will be analyzed using SPSS with significance set at p < 0.05. The study may support the use of cost-effective, noninvasive breathing techniques for improving pulmonary function and quality of life in COPD patients.

详细描述

The respiratory ailment known as chronic obstructive pulmonary disease (COPD) is becoming more and more common all over the world. It is characterized by a partiallyvolatile airway blockage. It is characterized by growing and ongoing dyspnea, persistent coughing and sputum production. Chronic cough and sputumare separaterisk factors for early death from COPD, and they are often closely associated withexacerbation. Alternate nostril breathing and bellows breath are two commontechnique which is based on pranyama,which is yogic practice of breath control. These techniques is utilize specific breathing pattern to in fluence the nervous system,energy flow and overall well being. The objective of this study is to findtheeffect of alternate nostril breathing and bellows breath on sputumclearance,pulmonary function test and quality of life among COPD patients. The study design will be randomized clinical trial. It will conducted at Punjab instituteof cardiology.sample size will be conducted through non-probability convenient sampling as per inclusion criteria participants will be randomly added intotwogroups. . Group A[alternate nostril breathing] and Group B[bellows breath]. bothintervention will be performed for 15 to 20 min/day for 3 to 4 weeks. Pre andpost intervention data will be collected. Outcome measures include sputumclearance,spiromter and health related quality of life questionnaire. Data will beanalyzed by using SPSS. Paired or Independent t-test will be used to comparevariables between the two groups and within the two groups, with significance set at p< 0.05. This study will provide evidence for the integration of noninvasive, cost effective strategies for the enhancement of PFT's and functional capacity and qualityof life.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
None

盲法说明

Because of the physical nature of the interventions, both participants and investigators will know which treatment is being given. No blinding will be applied.

入排标准

年龄范围
10 Years 至 —(Child, Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • diagnosed case of copd patients
  • Age group:above 10 years
  • Clinically stable
  • Able to understand or perform breathing exercise

排除标准

  • current acute pulmonary infection
  • History of pneumothorax or hemoptysis
  • Patients who was in stage 4 of functional classification of fatigue,palpation,dyspnea or anginal pain

结局指标

主要结局

Forced Vital Capacity

时间窗: Baseline and after 4 weeks of intervention

Forced Vital Capacity (FVC) will be measured in liters (L) using spirometry. FVC represents the maximum volume of air that can be forcefully exhaled after a maximal inspiration.

Forced Expiratory Volume in One Second

时间窗: Baseline and after 4 weeks of intervention

Forced Expiratory Volume in One Second (FEV₁) will be measured in liters (L) using spirometry. FEV₁ represents the volume of air exhaled during the first second of a forced expiratory maneuver.

FEV₁/FVC ratio

时间窗: Baseline and after 4 weeks of intervention

The FEV₁/FVC ratio will be expressed as a percentage (%) and calculated from spirometric measurements to assess the degree of airflow limitation

Health-Related Quality of Life

时间窗: Baseline and after 4 weeks of intervention

The HRQOL (Health-Related Quality of Life) questionnaire is a tool usedtoassess an individual's overall well-being, focusing on how their health impacts their daily life. It's a 14-item questionnaire developed by the Centers for DiseaseControl and Prevention (CDC) that explores physical, mental, and social healthdomains

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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