An Etiopathological Study Of Smriti Vibhramsha With Special Reference To Subjective Cognitive Impairment And Comparative Therapeutic Evaluation Of Amalakyadi Rasayana And Guduchyadi Rasayana In Its Management

Lifestyle changes and stressful circumstances has altered the psychological equilibrium of man. Hence, mental health promotion and management of various psychological and psychosomatic disorders are necessary. So, it is the need of the era to interpret the ancient concepts of Smriti with respect to modern medical and psychological sciences.

SCI has recently attracted renewed attention on the assumption that it could be the first notable manifestation in the preclinical stage of Alzheimer’s disease and dementia. In light of the projected increase of people living with dementia all over the world, there is a strong interest in early risk stages that may allow for early intervention or the prevention of dementia.

At present, many modern drugs which are available for various mental disorders are not safe to use because of their serious adverse effects. Ayurveda considers ageing as an inevitable part of life which can be delayed and its ill effects can be minimized by use of specific therapeutic interventions like rasayana. Rasayana has the potential to tackle the problems of neurodegeneration and its effect on cognition, thereby enhancing the quality of life of a person.

RESEARCH QUESTION a. What are the etiopathological factors contributing to Smriti vibhramsa with special reference to Subjective Cognitive Impairment in present time? b. Is there any difference in the efficacy of Amalakyadi rasayana and Guduchyadi rasayana in the patients of Smritikshaya with special reference to Subjective Cognitive Impairment?

HYPOTHESIS

Null Hypothesis [Ho]

There is no difference in the efficacy of Amalakyadi rasayana and Guduchyadi rasayana in the patients of Smriti vibhramsa with special reference to Subjective Cognitive Impairment.

Alternative Hypothesis [HA]

There is difference in the efficacy of Amalakyadi rasayana and Guduchyadi rasayana in the patients of Smriti vibhramsa with special reference to Subjective Cognitive Impairment.

AIMS

To assess and compare the therapeutic efficacy of Amalakyadi rasayana and Guduchyadi rasayana in the management of Smriti vibhramsa with special reference to Subjective Cognitive Impairment.

OBJECTIVES

Primary objectives To assess the comparative therapeutic efficacy of Amalakyadi rasayana and Guduchyadi rasayana in the management of Smriti vibhramsa with special reference to Subjective Cognitive Impairment.

Secondary objectives

To study the etiopathogenesis of Smriti vibhramsa with special reference to Subjective Cognitive Impairment.

To assess the therapeutic efficacy of Amalakyadi rasayana in the management of Smriti vibhramsa with special reference to Subjective Cognitive Impairment.

To assess the therapeutic efficacy of Guduchyadi rasayana in the management of Smriti vibhramsa with special reference to Subjective Cognitive Impairment.