Development of a Spinal Cord Injury-specific Exercise-based Capacity
试验速览
- 阶段
- 不适用
- 入组人数
- 6
- 试验地点
- 1
- 主要终点
- Peak VO2 (volume oxygen) output during exercise
研究概览
简要总结
Currently, those with spinal cord injury (SCI) demonstrate increased prevalence of obesity (75%) cardiovascular disease (30 - 50%), type II diabetes (21%) and osteoporosis in the legs (100%) when compared to the general population. It is important to identify the modes and intensities of exercise most likely to generate a reduction in these inactivity-related diseases in this population.
Therefore, the main purpose of this pilot research project is to implement and test a form of a spinal cord injury-specific exercise, known as FES rowing (FES: functional electrical stimulation).
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Have a spinal cord injury, C5-T12 (level), AIS A-D (severity)
- •Be aged 18-75 for duration of study
- •Medically stable and healthy enough to complete exercise requirements
- •Willing and able to complete the at-home training requirements as prescribed
- •Willing and able to complete the exercise sessions as prescribed
- •Willing and able to complete the VO2 testing throughout the study
- •Willing and able to complete the DEXA (Dual-energy X-ray absorptiometry) scans during the study
- •Able to understand and follow written or verbal instructions from study staff
排除标准
- •Current pressure ulcer(s) at sites of electrical stimulation
- •Previous spontaneous or low-impact leg fracture
- •Previous diagnosis of cardiovascular disease (ie enlarged heart, heart murmur)
- •Unsatisfactory results of EKG (electrocardiogram) screening test
- •Known thyroid dysfunction
- •Kidney disease
- •Blood pressure > 140/90 mmHg
- •Currently taking blood pressure medication
- •History of epilepsy
- •Current hand, arm or shoulder injury
- •Current deep vein thrombosis
- •Implanted electronic cardiac device (pace maker, defibrillator, etc)
- •Ventilator-dependent
- •Unable to follow written and verbal instructions
结局指标
主要结局
Peak VO2 (volume oxygen) output during exercise
时间窗: 24 weeks compared to baseline
Peak VO2 testing will be performed before beginning rower training and again at the end of the 24 weeks of training. Testing will be performed with an arm ergometer, rowing without electrical stimulation, and rowing with electrical stimulation. This will assess energy use, time to fatigue, and perceived exertion.
次要结局
- Leg EMG (electromyogram) while rowing(Throughout study (up to 36 weeks))
- Body composition(24 weeks compared to baseline)
研究者
Kristine Cowley
Assistant Professor
University of Manitoba