The Effect of Supplementation of Flaxseed, Hesperidin, Flaxseed and Hesperidin Together in Metabolic Syndrome and Its Components: A Randomized, Controlled Study
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 100
- 试验地点
- 2
- 主要终点
- Metabolic syndrome: Number of participants with treated metabolic syndrome
研究概览
简要总结
To study the effects of Hesperidin, flaxseed and both together in patients with metabolic syndrome, 100 patients will be randomly allocated to one of following four groups: control group, hesperidin group (2 capsules Hesperidin), flaxseed group (30 gram flaxseed) or flaxseed-hesperidin group (2 capsules Hesperidin and 30 gram flaxseed) for 12 weeks; both groups will be advised to adherence the investigators' diet and exercise program too. At the first and the end of the intervention, metabolic factors will be assessed and compared between groups.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age of 18 to 70 years
- •having 3 of 5 of high blood sugar, hypertension, high TG, high waist circumference, low HD
排除标准
- •pregnancy or lactation
- •history of Cardiovascular disease, Pulmonary disease, Renal disease & Celiac disease; Cirrhosis
- •Following a program to lose weight in recent 3 mo
研究组 & 干预措施
hesperidin and flaxseed
1000 mg hesperidin as two capsules and 30 grams flaxseed
干预措施: hesperidin and flaxseed (Dietary Supplement)
control
no supplementation
干预措施: control (Other)
flaxseed
30 grams flaxseed
干预措施: flaxseed (Dietary Supplement)
hesperidin
1000 mg hesperidin as two capsules
干预措施: hesperidin (Dietary Supplement)
结局指标
主要结局
Metabolic syndrome: Number of participants with treated metabolic syndrome
时间窗: 12 weeks
Number of participants with treated metabolic syndrome
次要结局
未报告次要终点
研究者
Dr Azita Hekmatdoost
Principal Investigator
National Nutrition and Food Technology Institute