Is There a Benefit From Addition of Treadmill Walking to Diet Restriction in Psoriasis Women With PCOS?
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Psoariasis area and severity index
研究概览
简要总结
Women with psoriasis usually develop many complications including polysyctic ovarian syndrome (PCOS). Nowdays, diet restriction combimed with phsyical exercises may improve both problems
详细描述
Forty Women with psoriasis with PCOS will be enrolled to be catogrized to Group I or group II. Group I will enroll twenty females with PCOS and Psoriasis who will apply forty minutes walking on treadmill three times per week. Also Group I will follow low calorie diet and daily metformin for 12 weeks. Group II will will enroll twenty females with PCOS and Psoriasis who will follow low calorie diet and daily metformin for 12 weeks
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 35 Years 至 45 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •obese (class I) women
- •chronic plaque psoriasis
- •polyscytic ovarian syndrome
排除标准
- •cardiac dysfucntions
- •liver diseases
- •repsiratory disease
- •vascular diseases
结局指标
主要结局
Psoariasis area and severity index
时间窗: it will be measured after 12 weeks
is an index used to express the severity of psoriasis. It combines the severity (erythema, induration and desquamation) and percentage of affected area
次要结局
- insuiln(It will be measured after 12 weeks)
- ratio of luteinizing hormone and follicle-stimulating hormone(It will be measured after 12 weeks)
- body mass index(It will be measured after 12 weeks)
- waist circumference(It will be measured after 12 weeks)
- waist hip ratio(It will be measured after 12 weeks)
- testesterone(it will be measured after 12 weeks)
- Dehydroepiandrosterone(It will be measured after 12 weeks)
- Dermatology life Quality Index(It will be measured after 12 weeks)
- HOMA-IR(It will be measured after 12 weeks)
- high density lipoprotein(It will be measured after 12 weeks)
- low density lipoprotein(It will be measured after 12 weeks)
- systolic blood pressure(It will be measured after 12 weeks)
- diatolic blood pressure(It will be measured after 12 weeks)
- total cholesterol(It will be measured after 12 weeks)
- fasting blood glucose(It will be measured after 12 weeks)
- triglycerides(It will be measured after 12 weeks)
研究者
Ali Mohamed Ali ismail
lecturer of physical therapy for Cardiovascular, Respiratory disorder and Geriatrics, Faculty of Physical Therapy, Cairo University
Cairo University