ACTRN12619000322134尚未招募未知
The effect of cryoprecipitate, cryopreserved platelets and fresh platelet transfusions on measures of haemostasis in patients with thrombocytopenia.
Canberra Hospital0 个研究点目标入组 18 人开始时间: 2019年3月4日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 尚未招募
- 发起方
- 入组人数
- 18
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Non-randomised trial
- 主要目的
- Treatment
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- 18 Years 至 o limit（—）
- 性别
- All
入选标准
- •Have a diagnosis of a haematological neoplasm as defined in the WHO Classification of Haematological Neoplasms 2008 or aplastic anaemia;
- •* Be 18 years or older at the date of consent;
- •* Be able to provide informed consent, directly or by means of a facilitator or interpreter for those unable to read or understand English, respectively;
- •* Have a platelet count as measured by routine laboratory full blood of 10x109/L or less;
- •* Have no, or only minor (CTC grade 1 or 2) bleeding;
- •* Have no religious or other objection to blood product transfusion;
排除标准
- •* Unable to provide fully informed consent by reason of intellectual, mental or physical disability, or poor understanding of English, except where it can be corrected, such as by the use of a health care interpreter;
- •* Suspected immune thrombocytopenic purpura, thrombotic thrombocytopenic purpura or heparin induced thrombocytopenia;
- •* Acute Promyelocytic leukaemia;
- •* Paroxysmal nocturnal haemoglobinuria;
- •* Established diffuse intravascular coagulation;
- •* Serious active bleeding, defined as grade 3 or above by CTC Criteria;
- •* Where platelet transfusion is expected to be required as prophylaxis for a clinical procedure within 72 hours on enrolment;
- •* Where a treating clinician has prescribed that prophylactic transfusions be given at a platelet count higher than 10x109/L
- •* Antiplatelet therapy within the previous 5 days;
- •* Antithymocyte globulin therapy within the previous 7 days;
- •* Immune mediated refractoriness to platelet transfusion (HLA or HPA mediated);
- •* Prior venous or arterial thrombosis (proven or suspected transient ischaemic attack, stroke or acute coronary syndrome) within three months;
- •* Any prior idiopathic venous thrombosis;
- •* A history of long term anticoagulant therapy at the time of the study, an indication for long term anticoagulation (eg. atrial fibrillation, mechanical prosthetic valve), or where anticoagulation has been ceased or withheld due to thrombocytopenia.
- •* Clinical signs or symptoms suspicious for recent venous thromboembolism, unless investigations excluded this as a cause or an alternative cause has been established.
研究者
相似试验
招募中
不适用
Comparison of the effectiveness of cryopreserved versus fresh peripheral blood allogenic stem cell transplantation at Siriraj hospitalThe patients aged greater than 15 years who undergo allogenic stem cell transplantationThe effectiveness of cryopreserved , Fresh peripheral blood, Allogenic stem cell transplantationTCTR20240612001Siriraj Hospital Mahidol University108
进行中（未招募）
1 期
A clinical trial to study the effects of genetically modified patients' CD34+ cellsAdenosine deaminase (ADA) deficiency is an inherited disorder that damages the immune system and causes severe combined immunodeficiency (SCID). Children with SCID lack virtually all immune protection from bacteria, viruses, and fungi. They are prone to repeated and persistent infections that can be very serious or life-threatening. If not treated in a way that restores immune function, children with SCID usually live only a year or two.MedDRA version: 20.1Level: LLTClassification code 10066372Term: ADA deficiencySystem Organ Class: 100000004850EUCTR2017-001275-23-GBGreat Ormond Street Hospital for Children NHS Trust10
尚未招募
Unknown
Exploring the Impact of Blueberries on Postprandial Oxidative Stress After a High-Fat High-Carbohydrate Meal in Young Healthy MeACTRN12624001039572Monash University15
进行中（未招募）
4 期
Bone gain assessment using bone material and blood derived materialCTRI/2018/02/011799Department of Periodontology and Implantology
尚未招募
3 期
Effect of cold irrigation on post operative pain after single visit root canal treatmentCTRI/2024/04/065587Dr Naveen prasath