EUCTR2012-001589-13-GB进行中（未招募）不适用
The effect of Aspirin on REducing iNflammation in human in vivo model of Acute lung injury (ARENA) - Aspirin in a model of acute lung injury in healthy volunteers
适应症
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •1.Healthy non-smoking subjects
- •Are the trial subjects under 18? no
- •Number of subjects for this age range: 0
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 40
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range 5
排除标准
- •1.Age < 18 years
- •2.Pregnancy or breast feeding or woman of childbearing potential not using adequate contraception.
- •3.Participation in a clinical trial of an investigational medicinal product within 30 days
- •4.Consent declined
- •5.Aspirin or non steroidal anti-inflammatory (NSAID) use in the past 4 weeks
- •6.History of asthma
- •7.Known aspirin or NSAID hypersensitivity
- •8.History of peptic ulcer disease
- •9.Platelet count < 150 x 106/ml
- •10.Aspirin resistance
- •Aspirin resistance is uncommon and therefore it is not anticipated that it will have a significant impact on the study. However subjects who do not show a change in measures of aspirin responsiveness following aspirin will be excluded. Aspirin responsiveness will be measured by Optical Platelet Aggregometry
研究者
相似试验
已完成
不适用
The effects of aspirin on pro-inflammatory response in subjects with diabetes mellitusutritional, Metabolic, Endocrine: DiabetesNutritional, Metabolic, EndocrineDiabetesISRCTN45751416Department of Health (UK)120
已完成
不适用
Effects of aspirin on markers of inflammation and coagulation in subclinical atherosclerosis in type 2 diabetic subjectsDiabetes mellitus type 2 (DM type 2)Nutritional, Metabolic, EndocrineNon-insulin dependant diabetesISRCTN84139732eiden University Medical Centre (LUMC) (Netherlands)40
已完成
2 期
Effect of administration low dose aspirin on pregnancy outcomeIRCT2014042017365N1rmia University of Medical Sciences200
已完成
2 期
The Effect of Aspirin on REducing iNflammation in Human in Vivo Model of Acute Lung InjuryAcute Lung InjuryNCT01659307Belfast Health and Social Care Trust33
已完成
3 期
The effect of Low-dose Aspirin in the Prevention of Gastric CancerGastric Cancer.Malignant neoplasm of stomachIRCT201105082032N3Ministry of Health and Medical Education21,000