Eating Behavior in Patients With Eosinophilic Esophagitis.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- Mayo Clinic
- 入组人数
- 31
- 试验地点
- 1
- 主要终点
- Observed eating session
研究概览
简要总结
Is there a difference in the eating process for patients with active Eosinophilic Esophagitis (EoE) and those with inactive disease?
详细描述
Eosinophilic esophagitis (EoE) patients develop adapted eating behaviors to prevent symptoms. These patients tend to cut their food small, chew extensively, take copious liquids with meals, and avoid foods that cause symptoms. No studies to date have directly evaluated these eating behaviors in patients with EoE with observation. Furthermore, none of the investigators' current metrics for patient symptom assessment visually evaluate the eating process nor are they compared before and after treatment. As a result, it is unclear if a patient's subjective perception of their eating difficulties and improvement matches with objective measures.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •18 years of age and older
- •Patients suspected to have Eosinophilic Esophagitis
- •Patients being treated for EoE with PPI or a steriod
- •EoE patients that are in remission by having less than 22 on the EEsAI questionnaire
- •Controls, patients that do not have EoE or other swallowing issues
排除标准
- •Clinical evidence of infectious process potentially contributing to dysphagia (candidiasis, CMV,herpes)
- •Other cause of dysphagia identified at endoscopy (reflux esophagitis, stricture, web, ring, achalasia, esophageal neoplasm)
- •EoE patients that do not eat sandwiches or feel they could not eat a sandwich.
结局指标
主要结局
Observed eating session
时间窗: 15-90 minutes
number of bites of patient's with EoE and controls eating a Jimmy John's sandwich
次要结局
- Food slowness during eating session(15-90 minutes)
- Water during eating session(15-90 minutes)
- Eosinophilic Esophagitis activity Index (EEsAI) questionnaire(10-15 minutes)
- Eosinophilic Esophagitis Quality of Life questionnaire(10-15 minutes)
研究者
Jeffrey A Alexander
Principal Investigator
Mayo Clinic