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临床试验/NL-OMON28273
NL-OMON28273已完成不适用

Evaluation of the CAP-value for quantitating liver steatosis in obese children using MRS-PDFF as reference standard.

Amsterdam UMC, location AMC, Department of Radiology & Nuclear Medicine0 个研究点目标入组 60 人开始时间: 待定最近更新:

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
60

研究概览

简要总结

/A

研究设计

研究类型
Observational

入排标准

入选标准

  • Written informed consent from parent(s) and subject (when >12 years of age)
  • - For current patients:
  • Clinically suspected or high risk profile of hepatic steatosis based on at least one of the following:
  • - abnormal echogenicity of liver in ultrasonography;
  • - elevated serum transaminases levels;
  • - high BMI (>+3 z-score) and/or waist circumference (>95 percentile);
  • - insulin resistance.
  • - For patients no longer in active follow-up:
  • Liver steatosis detected during follow-up in this clinic in the last 3 years

排除标准

  • - Age <8 and >18 years
  • - The need for anaesthesia during the MRI examination.
  • - General contra-indications for MRI scanning (use of MRI checklist, see document E4)
  • - Known focal liver lesion(s) in the right liver lobe (proven with histology results or imaging)
  • - Known concomitant liver disorders

研究者

发起方
Amsterdam UMC, location AMC, Department of Radiology & Nuclear Medicine

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