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临床试验/NCT06419569
NCT06419569尚未招募不适用

Efficacy of High Power Laser Versus Low Level Laser in Ultrasonographic and Functional Outcomes in Patients With Knee Osteoarthritis

Cairo University0 个研究点目标入组 90 人开始时间: 2024年5月30日最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
入组人数
90
主要终点
hyaline cartilage thickness assessment

研究概览

简要总结

this study will be conducted to compare between high power laser and low-intensity laser on ultrasonographic and functional outcomes in patients with knee osteoarthritis

详细描述

Osteoarthritis (OA) is a major source of pain, disability, and socioeconomic cost worldwide. The epidemiology of the disorder is complex and multifactorial, with genetic, biological, and biomechanical components. It is estimated that 63 to 85 percent of Americans over age 65 have radiographic signs of OA and that 35 to 50 percent have symptoms of pain, stiffness or limitation of motion. Between 9 and 12 percent of elderly Americans (approximately 3 million people) have enough impairment from OA that they cannot perform their major activities, and half of these individuals are totally disabled (confined to bed or a wheelchair). High power laser therapy (HPL) that involves higher-intensity laser radiation is a new, painless, and powerful modality that showed significant results in pain reduction. One of the modalities commonly used by clinicians was Low Level Laser Therapy introduced as an alternative, safe and non-invasive treatment for OA about 30 years ago.A more recent systemic review investigated the effects of low-level and high-intensity laser therapy as adjunctive to rehabilitation exercise on pain, stiffness and function in knee osteoarthritis and concluded that Both LLLT and HPL are beneficial as adjuncts to rehabilitation exercise in the management of knee OA. Based on an indirect comparison, the HPL and exercise seems to have higher efficacy in reducing knee pain and stiffness, and in increasing function. To confirm this finding, a direct comparative investigation of the two types of laser therapy may be necessary. ninety patients with knee osteoarthritis will be assigned randomly to three groups; the first experimental will receive high power laser plus conventional physical therapy, second one will receive low-intensity laser and traditional physical therapy, finally, the third group will receive traditionally therapy only

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Double (Investigator, Outcomes Assessor)

盲法说明

opaque sealed envelop

入排标准

年龄范围
45 Years 至 75 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • X-ray stages II and III osteoarthritis
  • Age between 45 and 75 years.
  • BMI equal to or less than 35.

排除标准

  • Unwillingness to participate in the study.
  • Uncompleted evaluation/treatment programs.
  • Any damage to the knee joint during the study.
  • Using any treatment other than prescribed therapeutic protocols.

结局指标

主要结局

hyaline cartilage thickness assessment

时间窗: up to eight weeks

utrasonographe device will be used to assess hyaline cartilage thickness

osteophyte diameter

时间窗: up to eight weeks

ultrasonographe device will be used to assess the osteophyte diameter

次要结局

  • knee range of motion(up to eight weeks)
  • pressure pain threshold(up to eight weeks)
  • knee function(up to eight weeks)
  • pain intensity(up to eight weeks)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Nabil Mahmoud Ismail Abdel-Aal

principle investigator nabil mahmoud ismail abdel-aal

Cairo University

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