One night of partial sleep restriction: effects on metabolism, mood and stress responsiveness - Metabolism and stress after one night of partial sleep restriction

eids Universitair Medisch Centrum0 个研究点目标入组 33 人开始时间: 待定最近更新: 2024年4月23日

适应症

试验速览

暂无简介。

•- Informed consent
•- Caucasian men
•- Age between 18 and 55 years
•- BMI between 20 and 25 kg/m2 (equally divided over the range, so ideally n=12 in BMI categories 20 -25; 25 - 30; 30 - 35 kg/m2)

•Active endocrine disease (e.g. diabetes mellitus type 1 and type 2, thyroid disease, Cushing*s disease and lipid-associated disorders such as FH)
•- Fasting glucose >7.0 mmol/L
•- Severe chronic disease (e.g. chronic liver or kidney disease)
•- Severe insomnia, sleep disorders or exceptional habitual sleep duration (<6 or >10 h).
•- Medication use including the following: lipid lowering drugs, glucocorticoids, sleep medication, hormone replacement, glucose lowering drugs, insulin therapy (last 6 weeks), anticoagulants
•- Recent time zone travel (last 6 weeks)
•- Shift work (last 6 weeks)
•- Severe alcohol use (>21 units/week)
•- Psychiatric disease
•- Drug abuse
•- Recent participation to another nutritional or biomedical trial (last 6 weeks)
•- Taking medication, which may interfere with study measurements, as judged by the responsible physician
•- Reported weight loss or weight gain (10%) in the last six months prior to the pre-study screening
•- Clinically relevant abnormalities in clinical chemistry at screening (to be judged by the study physician)
•- Reported use of any nicotine containing products in the six months preceding the study and during the study itself;
•- Extreme strenuous exercise during last 3 months, as judged by responsible physician
•- Excessive sunbathing during the last 3 months, as judged by responsible physician

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